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1.3.1.105: 2-methylene-furan-3-one reductase

This is an abbreviated version!
For detailed information about 2-methylene-furan-3-one reductase, go to the full flat file.

Reaction

4-hydroxy-2,5-dimethylfuran-3(2H)-one
+
NADP+
=
4-hydroxy-5-methyl-2-methylenefuran-3(2H)-one
+
NADPH
+
H+

Synonyms

FaEO, SIEO

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.105 2-methylene-furan-3-one reductase

Crystallization

Crystallization on EC 1.3.1.105 - 2-methylene-furan-3-one reductase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
crystallisation in complex with NADPH and 4-hydroxy-2,5-dimethyl-3(2H)-furanone or in complex with NADPH and 4-hydroxy-5-methyl-3(2H)-furanone. The crystal structure of FaEO was solved by molecular replacement using a published X-ray structure of a quinone oxidoreductase from Thermus thermophilus. The structure belongs to the zinc-independent medium chain dehydrogenase/reductase family