1.3.1.107: sanguinarine reductase
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For detailed information about sanguinarine reductase, go to the full flat file.
Reaction
Synonyms
SARED1
ECTree
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Systematic Name
Systematic Name on EC 1.3.1.107 - sanguinarine reductase
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dihydrosanguinarine:NAD(P)+ oxidoreductase
The enzyme, purified from the California poppy (Eschscholzia californica), is involved in detoxifying the phytoalexin sanguinarine produced by poppy itself (cf. EC 1.5.3.12, dihydrobenzophenanthridine oxidase), when it binds to the cell wall of the poppy cell. The reaction with NADPH is up to three times faster than that with NADH at low concentrations (<10 uM) of the dinucleotide. At higher concentrations the reaction with NADPH is inhibited but not that with NADH [1].