1.3.1.112: anthocyanidin reductase [(2S)-flavan-3-ol-forming]

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For detailed information about anthocyanidin reductase [(2S)-flavan-3-ol-forming], go to the full flat file.

Reaction

Synonyms

ANR, anthocyanidin reductase ((2S)-flavan-3-ol-forming)

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.1 With NAD⁺ or NADP⁺ as acceptor

                1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming]

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Results	in table
5	AA Sequence
3	Cloned(Commentary)
2	Cofactor
1	Crystallization (Commentary)
1	Expression
1	Inhibitors
2	KM Value [mM]
1	Molecular Weight [Da]
8	Organism
2	pH Optimum
2	Reaction
8	Reference
8	Source Tissue
13	Substrates and Products (Substrate)
1	Subunits
4	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Systematic Name

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Systematic Name on EC 1.3.1.112 - anthocyanidin reductase [(2S)-flavan-3-ol-forming]

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SYSTEMATIC NAME

IUBMB Comments

(2S)-flavan-3-ol:NAD(P)+ oxidoreductase

The enzyme, characterized from Vitis vinifera (grape), participates in the flavonoid biosynthesis pathway. It catalyses the double reduction of anthocyanidins, producing a mixture of (2S,3S)- and (2S,3R)-flavan-3-ols. The enzyme catalyses sequential hydride transfers to C-2 and C-4, respectively. Epimerization at C-3 is achieved by tautomerization that occurs between the two hydride transfers. cf. EC 1.3.1.77, anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming].