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1.3.1.114: 3-dehydro-bile acid DELTA4,6-reductase

This is an abbreviated version!
For detailed information about 3-dehydro-bile acid DELTA4,6-reductase, go to the full flat file.

Reaction

12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA
+
NAD+
=
12alpha-hydroxy-3-oxochol-4,6-dien-24-oyl-CoA
+
NADH
+
H+

Synonyms

BaiN, CLOSCI_00523

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.114 3-dehydro-bile acid DELTA4,6-reductase

Substrates Products

Substrates Products on EC 1.3.1.114 - 3-dehydro-bile acid DELTA4,6-reductase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NAD+
12alpha-hydroxy-3-oxochol-4,6-dien-24-oyl-CoA + NADH + H+
show the reaction diagram
12alpha-hydroxy-3-oxocholan-24-oyl-CoA + NAD+
12alpha-hydroxy-3-oxochol-4-en-24-oyl-CoA + NADH + H+
show the reaction diagram
3-oxochol-4-en-24-oyl-CoA + NAD+
3-oxochol-4,6-dien-24-oyl-CoA + NADH + H+
show the reaction diagram
3-oxocholan-24-oyl-CoA + NAD+
3-oxochol-4-en-24-oyl-CoA + NADH + H+
show the reaction diagram