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1.3.1.118: meromycolic acid enoyl-[acyl-carrier-protein] reductase

This is an abbreviated version!
For detailed information about meromycolic acid enoyl-[acyl-carrier-protein] reductase, go to the full flat file.

Word Map on EC 1.3.1.118

Reaction

a meromycolyl-[acyl-carrier protein]
+
NAD+
=
a trans-DELTA2-meromycolyl-[acyl-carrier protein]
 +
NADH
 +
H+

Synonyms

2-trans-enoyl-ACP reductase, 2-trans-enoyl-ACP(CoA) reductase, 2-trans-enoyl-acyl carrier protein reductase, enoyl acyl carrier protein reductase, enoyl acyl carrier protein reductase InhA, enoyl-ACP reductase, enoyl-ACP reductase InhA, enoyl-acyl carrier protein reductase, FAS-II enoyl reductase, FASII enoyl-ACP reductase, InhA, InhA Protein, MtInhA

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.118 meromycolic acid enoyl-[acyl-carrier-protein] reductase

KI Value

KI Value on EC 1.3.1.118 - meromycolic acid enoyl-[acyl-carrier-protein] reductase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.00012
2-(2-bromophenoxy)-5-hexylphenol
pH 6.8, 23°C
0.000052
2-(2-chlorophenoxy)-5-hexylphenol
pH 6.8, 23°C
0.016
2-(2-chlorophenoxy)-5-[(4-cyclopropyl-1H-1,2,3-triazol-1-yl)methyl]phenol
pH 6.8, 23°C
0.00022
2-(2-fluorophenoxy)-5-hexylphenol
pH 6.8, 23°C
0.006
2-(2-methylphenoxy)-5-[[4-(3-methylphenyl)-1H-1,2,3-triazol-1-yl]methyl]phenol
pH 6.8, 23°C
0.01
2-(4-hexyl-2-hydroxyphenoxy)benzonitrile
pH 6.8, 23°C
0.0071
2-(4-[[4-(2-bromoethyl)-1H-1,2,3-triazol-1-yl]methyl]-2-hydroxyphenoxy)benzonitrile
pH 6.8, 23°C
0.000022
2-(o-tolyloxy)-5-hexylphenol
pH 6.8, 23°C
0.028
2-[2-hydroxy-4-[(4-methyl-1H-1,2,3-triazol-1-yl)methyl]phenoxy]benzonitrile
pH 6.8, 23°C
0.0063
2-[4-[(4-cyclohexyl-1H-1,2,3-triazol-1-yl)methyl]-2-hydroxyphenoxy]benzonitrile
pH 6.8, 23°C
0.083
2-[4-[(4-cyclopentyl-1H-1,2,3-triazol-1-yl)methyl]-2-hydroxyphenoxy]benzonitrile
pH 6.8, 23°C
0.099
2-[4-[(4-cyclopropyl-1H-1,2,3-triazol-1-yl)methyl]-2-hydroxyphenoxy]benzonitrile
pH 6.8, 23°C
0.05
2-[4-[(4-ethyl-1H-1,2,3-triazol-1-yl)methyl]-2-hydroxyphenoxy]benzonitrile
pH 6.8, 23°C
0.00021
5-hexyl-2-(2-methylphenoxy)phenol
pH 6.8, 23°C
0.0000094
5-hexyl-2-phenoxyphenol
pH and temperature not specified in the publication
0.0000011
5-octyl-2-phenoxyphenol
pH and temperature not specified in the publication
0.0000118
5-pentyl-2-phenoxyphenol
pH and temperature not specified in the publication
0.00003
5-tetradecyl-2-phenoxyphenol
pH and temperature not specified in the publication
0.017
5-[(4-cyclopropyl-1H-1,2,3-triazol-1-yl)methyl]-2-(2-methylphenoxy)phenol
pH 6.8, 23°C
0.11
5-[(4-ethyl-1H-1,2,3-triazol-1-yl)methyl]-2-(2-methylphenoxy)phenol
pH 6.8, 23°C
0.0019
5-[[4-(4-chlorophenyl)-1H-1,2,3-triazol-1-yl]methyl]-2-(2-methylphenoxy)phenol
pH 6.8, 23°C
0.00013
isoniazid-NADP
pH 7.0, temperature not specified in the publication
1.8
N-[(1-[[3-hydroxy-4-(2-methylphenoxy)phenyl]methyl]-1H-1,2,3-triazol-4-yl)methyl]cyclopropanecarboxamide
pH 6.8, 23°C
0.0002
triclosan
pH and temperature not specified in the publication