1.3.1.13: prephenate dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about prephenate dehydrogenase (NADP+), go to the full flat file.

Reaction

Synonyms

11415867, CM-PD, MtPDH1, PD-CM-PDT, PDH1, PRDH, prephenate (nicotinamide adenine dinucleotide phosphate) dehydrogenase, prephenate dehydrogenase, prephenate-pretyrosine dehydrogenase, tyrA, TyrAp, XD72_2094

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.1 With NAD⁺ or NADP⁺ as acceptor

                1.3.1.13 prephenate dehydrogenase (NADP+)

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All data fields related to EC 1.3.1.13

Results	in table
900	AA Sequence
1	CAS Registry Number
4	Cloned(Commentary)
20	Cofactor
3	General Information
12	Inhibitors
18	kcat/KM [mM/s]
2	Ki Value [mM]
35	KM Value [mM]
2	Localization
5	Molecular Weight [Da]
26	Natural Substrates/ Products (Substrates)
40	Organism
3	Pathway
8	PDB ID
3	pH Optimum
1	pH Range
1	pH Stability
21	Protein Variants
6	Purification (Commentary)
1	Reaction
4	Reaction Type
39	Reference
11	Source Tissue
1	Specific Activity [micromol/min/mg]
30	Substrates and Products (Substrate)
3	Subunits
19	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
4	Temperature Stability [°C]
18	Turnover Number [1/s]

KM Value

KM Value on EC 1.3.1.13 - prephenate dehydrogenase (NADP+)

for references in articles please use BRENDA:EC1.3.1.13

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KM VALUE [mM]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

3.29

L-arogenate

Methanothrix harundinacea

A0A101IGG2

mutant Q227E, pH 7.6, temperature not specified in the publication

763088

0.561 - 3.3

NAD+

2 entries

0.005 - 0.36

NADP+

7 entries

0.033 - 5.2

prephenate

25 entries

0.561

NAD+

Ignicoccus hospitalis

A8AAX2

at pH 8.0 and 80°C

740420

3.3

NAD+

Nanoarchaeum equitans

-

at pH 8.0 and 80°C

740420

0.005

NADP+

Acinetobacter calcoaceticus

-

-

390560

0.012

NADP+

Vigna radiata

-

pretyrosine as substrate

390557

0.014

NADP+

Vigna radiata

-

prephenate as substrate

390557

0.062

NADP+

Ignicoccus hospitalis

A8AAX2

at pH 8.0 and 80°C

740420

0.077

NADP+

Phaseolus vulgaris

-

-

390556

0.079

NADP+

Phaseolus vulgaris

-

-

390556

0.36

NADP+

Nanoarchaeum equitans

-

at pH 8.0 and 80°C

740420

0.033

prephenate

Acinetobacter calcoaceticus

-

-

390560

0.077

prephenate

Vigna radiata

-

-

390557

0.127

prephenate

Glycine max

-

at 37°C, pH not specified in the publication

741040

0.13

prephenate

Phaseolus vulgaris

-

-

390556

0.14

prephenate

Glycine max

-

mutant T206S, pH 7.5, 37°C

762908

0.17

prephenate

Glycine max

-

mutant T131S, pH 7.5, 37°C

762908

0.18

prephenate

Phaseolus vulgaris

-

-

390556

0.21

prephenate

Glycine max

-

mutant T131A, pH 7.5, 37°C

762908

0.22

prephenate

Glycine max

-

mutant Q130A, pH 7.5, 37°C

762908

0.223

prephenate

Medicago truncatula

-

at 37°C, pH not specified in the publication

741040

0.26

prephenate

Glycine max

-

mutant Q130S, pH 7.5, 37°C

762908

0.27

prephenate

Glycine max

-

wild-type, pH 7.5, 37°C

762908

0.29

prephenate

Glycine max

-

mutant H124N, pH 7.5, 37°C

762908

0.319

prephenate

Ignicoccus hospitalis

A8AAX2

at pH 8.0 and 80°C

740113

0.319

prephenate

Ignicoccus hospitalis

A8AAX2

with NAD+ as cosubstrate, at pH 8.0 and 80°C

740420

0.37

prephenate

Glycine max

-

mutant Q184A, pH 7.5, 37°C

762908

0.38

prephenate

Methanothrix harundinacea

A0A101IGG2

wild-type, pH 7.6, temperature not specified in the publication

763088

0.44

prephenate

Glycine max

-

mutant Q130E, pH 7.5, 37°C

762908

0.443

prephenate

Ignicoccus hospitalis

A8AAX2

with NADP+ as cosubstrate, at pH 8.0 and 80°C

740420

0.48

prephenate

Glycine max

-

mutant Q130D, pH 7.5, 37°C

762908

0.49

prephenate

Glycine max

-

mutant N222Q, pH 7.5, 37°C

762908

0.69

prephenate

Nanoarchaeum equitans

-

with NAD+ as cosubstrate, at pH 8.0 and 80°C

740420

0.73

prephenate

Nanoarchaeum equitans

-

with NADP+ as cosubstrate, at pH 8.0 and 80°C

740420

2.67

prephenate

Methanothrix harundinacea

A0A101IGG2

mutant Q227E, pH 7.6, temperature not specified in the publication

763088

5.2

prephenate

Glycine max

-

mutant S101A, pH 7.5, 37°C

762908