1.3.1.13: prephenate dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about prephenate dehydrogenase (NADP+), go to the full flat file.

Reaction

Synonyms

11415867, CM-PD, MtPDH1, PD-CM-PDT, PDH1, PRDH, prephenate (nicotinamide adenine dinucleotide phosphate) dehydrogenase, prephenate dehydrogenase, prephenate-pretyrosine dehydrogenase, tyrA, TyrAp, XD72_2094

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.1 With NAD⁺ or NADP⁺ as acceptor

                1.3.1.13 prephenate dehydrogenase (NADP+)

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Results

in table

900

AA Sequence

1

CAS Registry Number

4

Cloned(Commentary)

20

Cofactor

3

General Information

12

Inhibitors

18

kcat/KM [mM/s]

2

Ki Value [mM]

35

KM Value [mM]

2

Localization

5

Molecular Weight [Da]

26

Natural Substrates/ Products (Substrates)

40

Organism

3

Pathway

8

PDB ID

3

pH Optimum

1

pH Range

1

pH Stability

21

Protein Variants

6

Purification (Commentary)

1

Reaction

4

Reaction Type

39

Reference

11

Source Tissue

1

Specific Activity [micromol/min/mg]

30

Substrates and Products (Substrate)

3

Subunits

19

Synonyms

1

Systematic Name

2

Temperature Optimum [°C]

4

Temperature Stability [°C]

18

Turnover Number [1/s]

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TURNOVER NUMBER [1/s]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.7

L-arogenate

Methanothrix harundinacea

A0A101IGG2

mutant Q227E, pH 7.6, temperature not specified in the publication

763088

0.018 - 26.3

prephenate

17 entries

0.018

prephenate

Glycine max

-

mutant T206S, pH 7.5, 37°C

762908

0.052

prephenate

Glycine max

-

mutant Q184A, pH 7.5, 37°C

762908

0.055

prephenate

Glycine max

-

mutant Q130A, pH 7.5, 37°C

762908

0.06

prephenate

Glycine max

-

mutant T131S, pH 7.5, 37°C

762908

0.075

prephenate

Glycine max

-

mutant H124N, pH 7.5, 37°C

762908

0.122

prephenate

Glycine max

-

mutant T131A, pH 7.5, 37°C

762908

0.29

prephenate

Methanothrix harundinacea

A0A101IGG2

mutant Q227E, pH 7.6, temperature not specified in the publication

763088

0.5

prephenate

Glycine max

-

mutant N222Q, pH 7.5, 37°C

762908

0.583

prephenate

Glycine max

-

mutant Q130S, pH 7.5, 37°C

762908

2.44

prephenate

Methanothrix harundinacea

A0A101IGG2

wild-type, pH 7.6, temperature not specified in the publication

763088

2.83

prephenate

Glycine max

-

mutant Q130D, pH 7.5, 37°C

762908

3.83

prephenate

Glycine max

-

mutant Q130E, pH 7.5, 37°C

762908

15

prephenate

Ignicoccus hospitalis

A8AAX2

at pH 8.0 and 80°C

740113

16.3

prephenate

Glycine max

-

wild-type, pH 7.5, 37°C

762908

18.3

prephenate

Glycine max

-

mutant S101A, pH 7.5, 37°C

762908

21.8

prephenate

Medicago truncatula

-

at 37°C, pH not specified in the publication

741040

26.3

prephenate

Glycine max

-

at 37°C, pH not specified in the publication

741040