1.3.1.31: 2-enoate reductase

This is an abbreviated version!
For detailed information about 2-enoate reductase, go to the full flat file.

Word Map on EC 1.3.1.31

Reaction

Butanoate
+
NAD+
=
but-2-enoate
+
NADH
+
H+

Synonyms

Achr-OYE3, Achr-OYE4, acylate:NAD+ DELTA2 oxidoreductase, enoate reductase, ERED, ERED xenobiotic reductase B, KYE1, LacER, NADPH dehydrogenase 1, NCR, old yellow enzyme, OPR1, OPR3, reductase, 2-enoate, SYE-4, XenA, XenB, yellow enzyme, Yers-ER, YqjM

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.31 2-enoate reductase

Inhibitors

Inhibitors on EC 1.3.1.31 - 2-enoate reductase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-cyclohexen-1-one
-
the addition of 260 mM 2-cyclohexen-1-one leads to a more than 30fold decrease of the half-life at 30°C
2-methylbutenoate
-
in all reversed micellar solutions inhibition by the enoate is observed at an overall concentration of 0.5-5 mM, implying that a concentration of substrate equal to the Km value in aqueous solution may already cause inhibition in reversed micelles
3-Phenylpropionate
4-phenylbutanoate
Aliphatic carboxylates
-
-
aminobenzotriazole
-
slight inhibition
benzoate
dicoumarol
dimethyl (2E)-2-methylbut-2-enedioate
-
-
dimethyl (2R)-2-methylbutanedioate
-
-
dimethyl (2S)-2-methylbutanedioate
-
-
dimethyl (2Z)-2-methylbut-2-enedioate
-
-
dimethyl 2-methylidenebutanedioate
-
-
fumarate
Mersalyl
-
1 mM, complete inhibition
methyl viologen
-
-
Metyrapone
-
slight inhibition
morin
O2
-
in the reduced state the enzyme is inactivated in 1-2 min, about 3 h after the removal of oxygen, the activity is partially restored
p-hydroxymercuribenzoate
-
0.1 mM, complete inhibition
phenyl propionate
-
-
phenylacetate
reduced methyl viologen
-
-
additional information
-
not inhibited by 2-cyclohexanone
-