1.3.1.38: trans-2-enoyl-CoA reductase (NADPH)

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For detailed information about trans-2-enoyl-CoA reductase (NADPH), go to the full flat file.

Reaction

Synonyms

2-trans enoyl-ACP(CoA) reductase, ECR, EgTER1, enoyl reductase, InhA, MECR, MECR-1, mitochondrial 2-trans-enoyl-CoA/ACP reductase, mitochondrial 2-trans-enoyl-thioester reductase, NADPH-dependent trans-2-enoyl-CoA reductase, reductase, trans-enoyl coenzyme A, TER, trans-2-enoyl-CoA reductase, trans-2-enoyl-CoA reductase (NADPH)

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.1 With NAD⁺ or NADP⁺ as acceptor

                1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)

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Results	in table
1	Activating Compound
138	AA Sequence
1	CAS Registry Number
10	Cloned(Commentary)
18	Cofactor
5	Disease/ Diagnostics
2	Expression
5	General Information
1	General Stability
20	Inhibitors
6	Ki Value [mM]
16	KM Value [mM]
19	Localization
5	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
30	Organism
5	Pathway
18	PDB ID
2	pH Optimum
1	pH Range
1	pH Stability
17	Protein Variants
5	Purification (Commentary)
4	Reaction
4	Reaction Type
29	Reference
43	Source Tissue
10	Specific Activity [micromol/min/mg]
3	Storage Stability
46	Substrates and Products (Substrate)
5	Subunits
23	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
3	Temperature Stability [°C]
2	Turnover Number [1/s]

Specific Activity

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Specific Activity on EC 1.3.1.38 - trans-2-enoyl-CoA reductase (NADPH)

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SPECIFIC ACTIVITY [µmol/min/mg]

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

0.005

Rattus norvegicus

-

substrate crotonyl-CoA

390755

0.05

Rattus norvegicus

-

substrate trans-hexenoyl-CoA

390755, 390756

0.065

Rattus norvegicus

-

substrate trans-hexenoyl-CoA

390756

0.0752

Cavia porcellus

Q9JIF5

partially purified

390760

0.2

Caenorhabditis elegans

O45903, Q9XXC8

mutant cells over-expressiong MECR-1

706445

0.346

Cavia porcellus

Q9JIF5

purified recombinant enzyme

390760

0.49

Escherichia coli

-

partially purified enzyme

390749

20

Escherichia coli

-

purified enzyme

390748

3.21

Caenorhabditis elegans

O45903, Q9XXC8

cells overexpressing native Etr1p

706445