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1.3.1.57: phloroglucinol reductase

This is an abbreviated version!
For detailed information about phloroglucinol reductase, go to the full flat file.

Word Map on EC 1.3.1.57

Reaction

dihydrophloroglucinol
+
NADP+
=
phloroglucinol
 +
NADPH
 +
H+

Synonyms

PGR, PGRcl, PGRde, PGReu

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.57 phloroglucinol reductase

Inhibitors

Inhibitors on EC 1.3.1.57 - phloroglucinol reductase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,4,6-Trihydroxybenzoate
-
tested at 1.0 mM and under N2, 49% inhibition
6-Hydroxynicotinate
-
tested at 1.0 mM, 12% inhibition
8-hydroxyquinoline
-
enzyme preincubated with the inhibitor, 0.00166 mM, for 60 min at room temperature before the addition of the substrate, 83% inhibition
catechol
-
tested at 1.0 mM, 14% inhibition
CuCl2
-
tested at 0.1 mM, 100% inhibition
diethyldicarbonate
-
tested at 1.0 mM, 54% inhibition
EDTA
-
enzyme preincubated with the inhibitor, 0.00333 mM, for 60 min at room temperature before the addition of the substrate, 11% inhibition
gallate
-
tested at 1.0 mM and under N2, 24% inhibition
hydroquinone
-
tested at 1.0 mM and under N2, 31% inhibition
hydroxylamine
-
enzyme preincubated with the inhibitor, 0.00166 mM, for 60 min at room temperature before the addition of the substrate, 9% inhibition
iodacetate
-
enzyme preincubated with the inhibitor, 0.00166 mM, for 60 min at room temperature before the addition of the substrate, 21% inhibition
menadione
-
tested at 1.0 mM, 33% inhibition
N-ethylmaleimide
-
tested at 1.0 mM, 94% inhibition
NAD+
-
with 0.33 mM, 15% inhibition
NADH
-
with 0.33 mM, 11% inhibition
NADP+
-
with 0.33 mM, 38% inhibition
o-phenanthroline
-
enzyme preincubated with the inhibitor, 0.00166 mM, for 60 min at room temperature before the addition of the substrate, 71% inhibition
p-chloromercuribenzoate