1.3.1.6: fumarate reductase (NADH)

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For detailed information about fumarate reductase (NADH), go to the full flat file.

Word Map on EC 1.3.1.6

1.3.1.6

nitrate

malate

shewanella

fad

flavoproteins

fumarase

iron-sulfur

succinogenes

ascaris

flavocytochrome

helminth

oneidensis

wolinella

viologen

anthelmintic

frigidimarina

succinate-ubiquinone

tetraheme

menaquinol

narghji

thiabendazole

sdhcdab

c4-dicarboxylate

geobacter

flavinylation

succinate:quinone

dmsabc

hymenolepis

cyma

putrefaciens

medicine

drug development

Reaction

Synonyms

ABB37_00293, FRD, FRdABCD, FRDg, FRDm1, FRDm2, FRDS, Frds1p, fumarate reductase, KPA86010, KPK_2907, mitochondrial rhodoquinol-fumarate reductase, NADH-dependent fumarate reductase, NADH-FR, NADH-FRD, NADH-fumarate reductase, NFRD, QFR

ECTree

1 Oxidoreductases

1.3 Acting on the CH-CH group of donors

1.3.1 With NAD⁺ or NADP⁺ as acceptor

1.3.1.6 fumarate reductase (NADH)

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Results	in table
8	Activating Compound
846	AA Sequence
8	Application
1	CAS Registry Number
10	Cloned(Commentary)
68	Cofactor
3	Crystallization (Commentary)
57	Disease/ Diagnostics
2	Expression
11	General Information
2	General Stability
23	IC50 Value
86	Inhibitors
9	Ki Value [mM]
25	KM Value [mM]
34	Localization
6	Metals/Ions
3	Molecular Weight [Da]
36	Natural Substrates/ Products (Substrates)
77	Organism
2	Oxidation Stability
3	Pathway
4	PDB ID
10	pH Optimum
4	pH Range
1	pI Value
1	Posttranslational Modification
8	Protein Variants
12	Purification (Commentary)
2	Reaction
5	Reaction Type
67	Reference
26	Source Tissue
19	Specific Activity [micromol/min/mg]
2	Storage Stability
79	Substrates and Products (Substrate)
6	Subunits
60	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
24	Turnover Number [1/s]

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Cloned on EC 1.3.1.6 - fumarate reductase (NADH)

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Saccharomyces cerevisiae

655610

delta FDRg2, fumarate reductase deficiency mutant

Trypanosoma brucei

Q8ITL2

390844

expressed in Aspergillus saccharolyticus

Trypanosoma brucei

Q8ITL2

739918

expression in Saccharomyces cerevisiae

Leptomonas pyrrhocoris

A0A0N0E041

762767

gene fccA, expression of wild-type and mutant flavocytochrome enzymes in the enzyme-deficient strain DELTAfccA

Shewanella frigidimarina

654657

gene fccA, subcloning in Escherichia coli, expression of wild-type and mutant flavocytochrome enzymes in the enzyme-deficient strain DELTAfccA EG301

Shewanella frigidimarina

654680

gene FRDg, DNA sequence determination and analysis, gene expression inhibition wby RNAi, stem-loop sense/antisense molecules, expresssion of EGFP-tagged enzyme in trypanosomes, cell line EATRO1125.T7T

Trypanosoma brucei

Q5BU12, Q5BU14, Q8ITL2

656280

gene FRDm1, DNA sequence determination and analysis, gene expression inhibition wby RNAi, stem-loop sense/antisense molecules, expresssion of EGFP-tagged enzyme in trypanosomes, cell line EATRO1125.T7T

Trypanosoma brucei

Q5BU12, Q5BU14, Q8ITL2

656280

gene FRDm2, DNA sequence determination and analysis, gene expression inhibition wby RNAi, stem-loop sense/antisense molecules, expresssion of EGFP-tagged enzyme in trypanosomes, cell line EATRO1125.T7T

Trypanosoma brucei

Q5BU12, Q5BU14, Q8ITL2

656280

genes frdA, frdB, and frdC, organized in an operon, DNA sequence determination and analysis, subcloning in Escherichia coli, expression of mutant enzymes

Bacteroides fragilis

Q7X478, Q7X479, Q7X480

656728