1.3.1.86: crotonyl-CoA reductase

This is an abbreviated version, for detailed information about crotonyl-CoA reductase, go to the full flat file.

Reaction

Butanoyl-CoA
+
NADP+
=
(E)-but-2-enoyl-CoA
 +
NADPH
 +
H+

Synonyms

3-hydroxyacyl CoA reductase, acyl-CoA:NADP+ trans-2-oxidoreductase, bcd2, butanoyl-CoA:(acceptor) 2,3-oxidoreductase, butyryl coenzyme A dehydrogenase, butyryl dehydrogenase, butyryl-CoA dehydrogenase, butyryl-CoA dehydrogenase complex, CCR, CD1054, crotonyl CoA reductase, crotonyl coenzyme A reductase, crotonyl-CoA reductase, crotonyl-coenzyme A reductase, enoyl-coenzyme A reductase, ethylene reductase, short-chain acyl CoA dehydrogenase, short-chain acyl-coenzyme A dehydrogenase, trans-crotonyl CoA reductase, unsaturated acyl coenzyme A reductase, unsaturated acyl-CoA reductase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.86 crotonyl-CoA reductase

Cofactor

Cofactor on EC 1.3.1.86 - crotonyl-CoA reductase

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COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
FAD
-
in the absence of ferredoxin, a remarkable stimulation of crotonyl-CoA reduction by FAD is observed
Ferredoxin
-
butyryl-CoA dehydrogenase from C. difficile belongs to the subfamily of bifurcating enzymes capable of coupling the exergonic reduction of crotonyl-CoA by NAD Hwith the endergonic reduction of ferredoxin by NADH
-
NADPH