1.3.1.92: artemisinic aldehyde DELTA11(13)-reductase

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Reaction

Synonyms

artemisinic aldehyde DELTA11(13) double bond reductase2, artemisinic aldehyde DELTA11(13) double-bond reductase, artemisinic aldehyde DELTA11(13) reductase, Dbr2, double bond reductase 2, double-bond reductase 2

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.1 With NAD⁺ or NADP⁺ as acceptor

                1.3.1.92 artemisinic aldehyde DELTA11(13)-reductase

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Results	in table
1	Activating Compound
1	AA Sequence
4	Application
8	Cloned(Commentary)
8	Cofactor
6	Expression
4	General Information
5	kcat/KM [mM/s]
5	KM Value [mM]
1	Localization
1	Molecular Weight [Da]
8	Natural Substrates/ Products (Substrates)
14	Organism
3	Pathway
4	PDB ID
1	pH Optimum
2	pH Range
3	Protein Variants
1	Purification (Commentary)
1	Reaction
14	Reference
15	Source Tissue
19	Substrates and Products (Substrate)
17	Synonyms
1	Systematic Name
5	Turnover Number [1/s]

Cloned

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Cloned on EC 1.3.1.92 - artemisinic aldehyde DELTA11(13)-reductase

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

expressed in Nicotiana benthamiana

Artemisia annua

C5H429

765324

expression in Saccharomyces cerevisiae

Artemisia annua

C5H429

717776

gene DBR2, cloning, sequencing, and analysis of the promoter of the DBR2 gene, detailed overview. The activity of the artemisinic aldehyde DELTA11(13) reductase promoter is important for artemisinin yield in different chemotypes of Artemisia annua, quantitative real-time PCR expression analysis, overview

Artemisia annua

C5H429

746092

gene DBR2, overexpression in Artemisia annua under control of the CaMV 35S promoter via transfecton through Agrobacterium tumefaciens strain LBA4404 mediated leaf disc transformation, quantitative real-time PCR expression analysis, method evaluation

Artemisia annua

C5H429

744537

gene DBR2, quantitative real-time PCR expression analysis

Artemisia annua

C5H429

744543, 744971, 746262

gene DBR2, recombinant expression of the enzyme in transgenic Nicotiana tabacum plant leaf chloroplasts via transfection with Agrobacterium tumefaciens strain EHA105, nuclear genome transformation of homoplastomic plant

Artemisia annua

C5H429

745811