1.3.1.92: artemisinic aldehyde DELTA11(13)-reductase
This is an abbreviated version!
For detailed information about artemisinic aldehyde DELTA11(13)-reductase, go to the full flat file.
Word Map on EC 1.3.1.92
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1.3.1.92
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artemisinin
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annua
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artemisia
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trichomes
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cyp71av1
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amorpha-4,11-diene
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glandular
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trichome-specific
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antimalarial
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dihydroartemisinic
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hydroxylase
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malaria
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synthesis
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medicine
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drug development
- 1.3.1.92
- artemisinin
- annua
-
artemisia
- trichomes
- cyp71av1
- amorpha-4,11-diene
- glandular
-
trichome-specific
-
antimalarial
-
dihydroartemisinic
- hydroxylase
-
malaria
- synthesis
- medicine
- drug development
Reaction
Synonyms
artemisinic aldehyde DELTA11(13) double bond reductase2, artemisinic aldehyde DELTA11(13) double-bond reductase, artemisinic aldehyde DELTA11(13) reductase, Dbr2, double bond reductase 2, double-bond reductase 2
ECTree
1.3.1.92 artemisinic aldehyde DELTA11(13)-reductaseAdvanced search results
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results (Results
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17
Substrates Products
Substrates Products on EC 1.3.1.92 - artemisinic aldehyde DELTA11(13)-reductase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
(+)-carvone + NADH + H+
(1R,4S)-isodihydrocarvone + NAD+
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plus about 20% of (1S,4S)-dihydrocarvone
-
?
2E-nonenal + NADH + H+
nonanal + NAD+
about 12% of the activity with artemisinic aldehyde
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-
?
3beta-hydroxycostunolide + NADPH + H+
3beta-hydroxy-dihydroparthenolide + NADP+
-
-
-
?
artemisinic aldehyde + NADH + H+
(11R)-dihydroartemisinic aldehyde + NAD+
-
-
-
?
artemisinic aldehyde + NADPH + H+
dihydroartemisinic aldehyde + NADP+
-
-
-
?
parthenolide + NADPH + H+
dihydroparthenolide + NADP+
good substrate
-
-
?
artemisinic aldehyde + NADPH + H+
(11R)-dihydroartemisinic aldehyde + NADP+
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-
-
-
?
artemisinic aldehyde + NADPH + H+
(11R)-dihydroartemisinic aldehyde + NADP+
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-
-
?
artemisinic aldehyde + NADPH + H+
(11R)-dihydroartemisinic aldehyde + NADP+
double bond reductase 2 (DBR2) reduces the DELTA11(13) double bond of artemisinic aldehyde
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-
?
additional information
?
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no substrate: arteannuin B, artemisinic acid, artemisinic alcohol, artemisitene, coniferyl aldehyde, (2E)-nonenal, alpha-pinene, (+)-pulegone, and sabinone
-
-
?
additional information
?
-
-
no substrate: arteannuin B, artemisinic acid, artemisinic alcohol, artemisitene, coniferyl aldehyde, (2E)-nonenal, alpha-pinene, (+)-pulegone, and sabinone
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-
?
additional information
?
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GC-MS analysis of dihydroartemisinic acid synthesized in different plant varieties, overview
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-
?
additional information
?
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LC-MS/MS analysis of dihydroartemisinic acid synthesized in plants
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?
additional information
?
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the conversion of dihydroartemisinic acid to artemisinin is a non-enzymatic photochemical oxidation process
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-
?
