1.3.1.94: polyprenol reductase

This is an abbreviated version!
For detailed information about polyprenol reductase, go to the full flat file.

Word Map on EC 1.3.1.94

1.3.1.94

dolichols

polyprenols

pmm2-cdg

atp6v0a2

cis-prenyltransferase

coloboma

alpha-dihydrotestosterone

srd5as

medicine

Reaction

Synonyms

DFG10, PPRD, SDR5A3, SRD5A3, steroid 5alpha-reductase type 3

ECTree

1 Oxidoreductases

1.3 Acting on the CH-CH group of donors

1.3.1 With NAD⁺ or NADP⁺ as acceptor

1.3.1.94 polyprenol reductase

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Results	in table
2985	AA Sequence
1	Application
1	CAS Registry Number
3	Cloned(Commentary)
49	Disease/ Diagnostics
3	General Information
1	Localization
3	Natural Substrates/ Products (Substrates)
5	Organism
5	Pathway
1	pH Optimum
1	Reaction
5	Reference
1	Source Tissue
7	Substrates and Products (Substrate)
7	Synonyms
1	Systematic Name

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Reference on EC 1.3.1.94 - polyprenol reductase

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719005

Szkopinska, A.; Swiezewska, E.; Rytka, J.

Interplay between the cis-prenyltransferases and polyprenol reductase in the yeast Saccharomyces cerevisiae

Biochimie

271-276

2006

Saccharomyces cerevisiae

16213651

719256

Cantagrel, V.; Lefeber, D.J.; Ng, B.G.; Guan, Z.; Silhavy, J.L.; Bielas, S.L.; Lehle, L.; Hombauer, H.; Adamowicz, M.; Swiezewska, E.; De Brouwer, A.P.; Bluemel, P.; Sykut-Cegielska, J.; Houliston, S.; Swistun, D.; Ali, B.R.; Dobyns, W.B.; Babovic-Vuksanovic, D.; van Bokhoven, H.; Wevers, R.A.; Raetz, C.

SRD5A3 is required for converting polyprenol to dolichol and is mutated in a congenital glycosylation disorder

Cell

142

203-217

2010

Homo sapiens (Q9H8P0), Homo sapiens, Mus musculus (Q9WUP4)

20637498

719778

Sagami, H.; Kurisaki, A.; Ogura, K.

Formation of dolichol from dehydrodolichol is catalyzed by NADPH-dependent reductase localized in microsomes of rat liver

J. Biol. Chem.

268

10109-10113

1993

Rattus norvegicus

8486680

765622

Van Gelder, K.; Virta, L.K.A.; Easlick, J.; Prudhomme, N.; McAlister, J.A.; Geddes-McAlister, J.; Akhtar, T.A.

A central role for polyprenol reductase in plant dolichol biosynthesis

Plant Sci.

303

110773

2021

Solanum lycopersicum (A0A3Q7ETM3), Solanum lycopersicum

33487357