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1.3.1.B14: curacin A enoyl-acyl carrier protein reductase

This is an abbreviated version!
For detailed information about curacin A enoyl-acyl carrier protein reductase, go to the full flat file.

Reaction

(2E,4E,6E,10Z)-4-methyl-11-[2-[(1R,2S)-2-methylcyclopropyl]-4,5-dihydro-1,3-thiazol-4-yl]undeca-2,4,6,10-tetraenoyl-[acyl-carrier-protein]
+
NADPH
+
H+
=
(2E,4E,6E,10Z)-4-methyl-11-[2-[(1R,2S)-2-methylcyclopropyl]-4,5-dihydro-1,3-thiazol-4-yl]undeca-4,6,10-trienoyl-[acyl-carrier-protein]
+
NADP+

Synonyms

curacin enoyl reductase, CurK

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.1 With NAD+ or NADP+ as acceptor
                1.3.1.B14 curacin A enoyl-acyl carrier protein reductase

General Information

General Information on EC 1.3.1.B14 - curacin A enoyl-acyl carrier protein reductase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
physiological function
enzyme is involved in biosynthesis of anticancer agent curacin A