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1.3.2.3: L-galactonolactone dehydrogenase

This is an abbreviated version!
For detailed information about L-galactonolactone dehydrogenase, go to the full flat file.

Word Map on EC 1.3.2.3

Reaction

L-galactono-1,4-lactone
+
2 ferricytochrome c
=
L-ascorbate
 + 2 ferrocytochrome c + 2 H+

Synonyms

dehydrogenase, galactonolactone, ferricytochrome c oxidoreductase, galactono-1,4-lactone dehydrogenase, galactonolactone dehydrogenase, GALDH, GalL dehydrogenase, GalLDH, GLDase, GLDH, GLDH-A1, GLDH-B1, GLDH-D1, GLDH1, GLDHase, L-galactone-1,4-lactone dehydrogenase, L-galactono-1, 4-lactone dehydrogenase, L-galactono-1,4-lactone dehydrogenase, L-galactono-gamma-lactone dehydrogenase, L-GalLDH, L-GalLDH1, L-GalLDH2, LsL-GalLDH, RrGalLDH

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.2 With a cytochrome as acceptor
                1.3.2.3 L-galactonolactone dehydrogenase

Molecular Weight

Molecular Weight on EC 1.3.2.3 - L-galactonolactone dehydrogenase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
420000
-
three distinct GLDH containing protein complexes of 850, 470, and 420 kDa are discovered using a newly developed in gel GLDH activity assay and immunoblotting. Subunits of the novel 470 and 420 kDa complexes are identified by mass spectrometry. Like the 850-kDa complex, they also include complex I subunits
470000
-
three distinct GLDH containing protein complexes of 850, 470, and 420 kDa are discovered using a newly developed in gel GLDH activity assay and immunoblotting. Subunits of the novel 470 and 420 kDa complexes are identified by mass spectrometry. Like the 850-kDa complex, they also include complex I subunits
55000
-
mature enzyme, SDS-PAGE
56000
57110
predicted from the view that the FR/YA site is the cleavage point for the mature protein
58000
-
SDS-PAGE, monomeric form of GLDH
58760
-
predicted molecular mass of mature His-tagged enzyme
6800
immunoblotting, the pre-mature GalLDH with a mitochondrion-targeting signal
68800
-
theoretical value
850000
-
three distinct GLDH containing protein complexes of 850, 470, and 420 kDa are discovered using a newly developed in gel GLDH activity assay and immunoblotting. The 850-kDa complex represents the known smaller version of mitochondrial complex I. GLDH is shown to be attached to the membrane arm of the 850-kDa complex I