1.3.3.3: coproporphyrinogen oxidase

This is an abbreviated version!
For detailed information about coproporphyrinogen oxidase, go to the full flat file.

Word Map on EC 1.3.3.3

1.3.3.3

heme

protoporphyrinogen

coproporphyria

protoporphyrin

porphyria

ferrochelatase

uroporphyrinogen

5-aminolevulinic

porphobilinogen

tetrapyrrole

porphyrinogens

medicine

oxygen-independent

coproporphyrinuria

mg-protoporphyrin

ala-pdt

delta-aminolaevulinic

uroporphyrin

cutanea

analysis

Reaction

+ 2 H+ =

+ 2 CO2 + 2 H2O

Synonyms

copro'gen oxidase, Coprogen oxidase, coproporphyinogen oxidase, coproporphyrinogen III oxidase, coproporphyrinogen oxidase, coproporphyrinogen-III oxidase, coproporphyrinogenase, COX, CPgen oxidase, CPGox, CPO, CPO III oxidase, CPOX, CPOX4, CPX, CPX1, CPX2, HEM13, Hem13p, HemF, HEMN1, KlHEM13, LIN2, LMM2, O2-dependent coproporphyrinogen III oxidase, oxygen-dependent coproporphyrinogen III oxidase, oxygen-dependent coproporphyrinogen-III oxidase, Sll1185

ECTree

1 Oxidoreductases

1.3 Acting on the CH-CH group of donors

1.3.3 With oxygen as acceptor

1.3.3.3 coproporphyrinogen oxidase

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Results	in table
40	Activating Compound
17573	AA Sequence
16	Application
1	CAS Registry Number
40	Cloned(Commentary)
11	Cofactor
3	Crystallization (Commentary)
210	Disease/ Diagnostics
5	Expression
34	General Information
5	General Stability
1	IC50 Value
71	Inhibitors
10	kcat/KM [mM/s]
1	Ki Value [mM]
108	KM Value [mM]
51	Localization
26	Metals/Ions
45	Molecular Weight [Da]
101	Natural Substrates/ Products (Substrates)
126	Organism
2	Oxidation Stability
9	Pathway
26	PDB ID
21	pH Optimum
3	pH Range
2	pH Stability
1	pI Value
103	Protein Variants
35	Purification (Commentary)
9	Reaction
5	Reaction Type
110	Reference
101	Source Tissue
19	Specific Activity [micromol/min/mg]
6	Storage Stability
201	Substrates and Products (Substrate)
34	Subunits
124	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]
58	Turnover Number [1/s]

KM Value

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KM Value on EC 1.3.3.3 - coproporphyrinogen oxidase

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0.002

3-[7,13-di(2-carboxy-ethyl)-17-benzyl-3,8,12,18-tetramethyl-porphyrinogen-2-yl]-propionic acid

Gallus gallus

390944

0.000011

3-[7,13-di(2-carboxy-ethyl)-17-ethyl-3,8,12,18-tetramethyl-porphyrinogen-2-yl]-propionic acid

Homo sapiens

at 37°C

688811

0.00088

3-[7,17-di(2-carboxy-ethyl)-13-benzyl-3,8,12,18-tetramethyl-porphyrinogen-2-yl]-propionic acid

Gallus gallus

390944

0.00085

3-[7,17-di(2-carboxy-ethyl)-13-ethyl-3,8,12,18-tetramethyl-porphyrinogen-2-yl]-propionic acid

Homo sapiens

at 37°C

688811

0.0001

3-[7-(2-carboxy-ethyl)-13,17-di-tert-butyl-3,8,12,18-tetramethyl-porphyrinogen-2-yl]-propionic acid

Gallus gallus

390944

0.011

3-[7-(2-carboxy-ethyl)-13,17-dibutyl-3,8,12,18-tetramethyl-porphyrinogen-2-yl]-propionic acid

Homo sapiens

at 37°C

688811

0.00056 - 0.00099

3-[7-(2-carboxy-ethyl)-13,17-diethyl-3,8,12,18-tetramethyl-porphyrinogen-2-yl]-propionic acid

2 entries

0.00035

3-[7-(2-carboxy-ethyl)-13,17-diisopropyl-3,8,12,18-tetramethyl-porphyrinogen-2-yl]-propionic acid

Gallus gallus

390944

0.011

3-[7-(2-carboxy-ethyl)-13,17-dipropyl-3,8,12,18-tetramethyl-porphyrinogen-2-yl]-propionic acid

Homo sapiens

at 37°C

688811

0.001

3-[7-(2-carboxy-ethyl)-3,8,12,13,17,18-hexamethyl-porphyrinogen-2-yl]-propionic acid

Gallus gallus

390944

0.000066 - 0.0151

Coproporphyrinogen III

4 entries

0.0009

coproporphyrinogen IV

Rattus sp.

390971

0.000066 - 0.32

Coproporphyrinogen-III

69 entries

0.00065 - 0.00083

coproporphyrinogen-IV

3 entries

0.00015 - 0.044

Harderoporphyrinogen

8 entries

0.00056 - 0.002

mesoporphyrinogen-VI

8 entries

0.0013

pentacarboxylate porphyrinogen 5dab

2 entries

0.029

pentacarboxylate porphyrinogen III

Rattus sp.

390971