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1.3.3.6: acyl-CoA oxidase

This is an abbreviated version!
For detailed information about acyl-CoA oxidase, go to the full flat file.

Word Map on EC 1.3.3.6

Reaction

acyl-CoA
+
O2
=
trans-2,3-dehydroacyl-CoA
 +
H2O2

Synonyms

3alpha,7alpha, 12alpha-trihydroxy-5beta-cholestanoyl-CoA oxidase, ACO, ACO I, ACO-A1, ACO-I, ACO-II, ACOX, ACOX-1, ACOX-1.1, ACOX-1.2, ACOX-1.3, ACOX-2, ACOX-3, ACOX1, ACOX1-3I, ACOX1a, ACOX1b, ACOX1–3II, ACOX2, ACOX3, ACX, ACX1, ACX1.2, ACX2, ACX3, ACX4, ACX5, acyl coenzyme A oxidase, acyl-CoA dehydrogenase, Acyl-CoA oxidase, acyl-CoA oxidase 1, acyl-CoA oxidase 1a, acyl-CoA oxidase 1b, acyl-CoA oxidase 2, acyl-CoA oxidase 4, acyl-CoA oxidase I, acyl-CoA oxidase-1, acyl-CoA oxidase-II, acyl-CoA-oxidase, acyl-coenzyme A oxidase, acyl-coenzyme A oxidase 1, acyl-coenzyme A oxidase 4, acyl-coenzyme A: oxygen oxidoreductase, AOX, AOX1, AOX2, Aox2p, AOX3, Aox3p, AOX4, aoxA, Aoxp, AtACX1, AtACX2, AtACX3, AtSACX, BRCACox, CrACX2, Cre05.g232002, fatty acyl-CoA oxidase, fatty acyl-coenzyme A oxidase, long chain acyl-CoA oxidase, long chain fatty acyl coenzyme A oxidase, long chain fatty acyl-CoA oxidase, long-chain-specific acyl-CoA oxidase 1, MCAD Y375K, MCOX, oxidase, acyl-coenzyme A, palmitoyl-CoA oxidase, peroxisomal acyl-coenzyme A oxidase, Peroxisomal fatty acyl-CoA oxidase, POX1, Pox1p, POX4, PpACX1, Pristanoyl-CoA oxidase, SCOX, short chain-specific acyl-CoA oxidase, short-chain acyl-CoA oxidase, straight chain acyl-CoA oxidase, straight-chain acyl-coenzyme A oxidase, THCA-CoA oxidase, THCCox, Trihydroxycoprostanoyl-CoA oxidase

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.3 With oxygen as acceptor
                1.3.3.6 acyl-CoA oxidase

Substrates Products

Substrates Products on EC 1.3.3.6 - acyl-CoA oxidase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
1,16-hexadecadioyl-CoA + O2
?
show the reaction diagram
-
-
-
-
?
16-hydroxy-palmitoyl-CoA + O2
?
show the reaction diagram
-
-
-
-
?
2-oxoheptadecyldethio-CoA + O2
?
show the reaction diagram
-
-
-
-
?
4,8,12-trimethyl-tridecanoyl-CoA + O2
?
show the reaction diagram
-
-
-
-
?
4-methyl-nonanoyl-CoA + O2
?
show the reaction diagram
-
-
-
-
?
6-phenyl-6-phenyl-hexanoyl-CoA + O2
?
show the reaction diagram
-
-
-
-
?
acyl-CoA + O2
trans-2,3-dehydroacyl-CoA + H2O2
show the reaction diagram
acyl-CoA + O2
trans-2-enoyl-CoA + H2O2
show the reaction diagram
-
assay at 25°C
-
-
ir
arachidoyl-CoA + O2
2-trans-eicosenoyl-CoA + H2O2
show the reaction diagram
-
-
-
-
?
behenoyl-CoA + O2
2-trans-docosenoyl-CoA + H2O2
show the reaction diagram
butyryl-CoA + O2
trans-2-butenoyl-CoA + H2O2
show the reaction diagram
cis-3-decenoyl-CoA + O2
?
show the reaction diagram
-
-
-
-
?
cis-3-hexenoyl-CoA + O2
?
show the reaction diagram
-
best substrate for the isomerase activity of the enzyme
-
-
?
cis-3-octenoyl-CoA + O2
?
show the reaction diagram
-
-
-
-
?
dec-4-cis-enoyl-CoA + O2
2-trans-4-cis-decadienoyl-CoA + H2O2
show the reaction diagram
dec-4-trans-enoyl-CoA + O2
2-trans-4-trans-decadienoyl-CoA + H2O2
show the reaction diagram
-
-
-
?
decanoyl-CoA + O2
trans-2,3-dehydrodecanoyl-CoA + H2O2
show the reaction diagram
-
-
-
?
decanoyl-CoA + O2
trans-2-decenoyl-CoA + H2O2
show the reaction diagram
dicarboxylic acid-CoAs with 6-16 carbon atoms + O2
?
show the reaction diagram
-
-
-
-
?
dodecanoyl-CoA + O2
(2E)-dodec-2-enoyl-CoA + H2O2
show the reaction diagram
dodecanoyl-CoA + O2
trans-dodec-2-enoyl-CoA + H2O2
show the reaction diagram
-
-
-
-
r
eicosapentaenoyl-CoA + O2
?
show the reaction diagram
-
-
-
-
?
furylpropionyl-CoA + O2
furylacryloyl-CoA + H2O2
show the reaction diagram
-
also oxidizes aromatic/heterocyclic ring-substituted chromogenic substrates
-
?
hexadecanedioyl-CoA + O2
?
show the reaction diagram
hexadecanoyl-CoA + O2
trans-2,3-dehydrohexadecanoyl-CoA + H2O2
show the reaction diagram
-
-
-
?
hexanoyl-CoA + O2
(2E)-hex-2-enoyl-CoA + H2O2
show the reaction diagram
indole-3-butyric acid-CoA + O2
?
show the reaction diagram
-
-
-
-
?
jasmonic acid-CoA + O2
?
show the reaction diagram
preferred substrate of ACX1
-
-
?
lauroyl-CoA + O2
trans-2-dodecenoyl-CoA + H2O2
show the reaction diagram
leukodiacetyl-2,7-dichlorofluorescein + O2
?
show the reaction diagram
-
-
-
-
?
lignoceroyl-CoA + O2
?
show the reaction diagram
linoleoyl-CoA + O2
2-trans-9-trans-12-trans-octadecatrienoyl-CoA + H2O2
show the reaction diagram
myristoyl-CoA + O2
trans-2-tetradecenoyl-CoA + H2O2
show the reaction diagram
nonanoyl-CoA + O2
trans-2-nonenoyl-CoA + H2O2
show the reaction diagram
-
-
-
-
?
octadecanoyl-CoA + O2
?
show the reaction diagram
preferred substrate of ACX2
-
-
?
octanoyl-CoA + O2
trans-2,3-dehydrooctanoyl-CoA + H2O2
show the reaction diagram
-
-
-
?
octanoyl-CoA + O2
trans-2-octenoyl-CoA + H2O2
show the reaction diagram
oleoyl-CoA + O2
2-trans-9-trans-octadecendienoyl-CoA + H2O2
show the reaction diagram
palmitoyl-CoA + O2
2-trans-hexadecenoyl-CoA + H2O2
show the reaction diagram
palmitoyl-CoA + O2
trans-2,3-dehydropalmitoyl-CoA
show the reaction diagram
palmitoyl-CoA + O2
trans-2,3-dehydropalmitoyl-CoA + H2O2
show the reaction diagram
pristanoyl-CoA + O2
trans-2,3-dehydropristanoyl-CoA + H2O2
show the reaction diagram
-
-
-
?
stearoyl-CoA + O2
trans-2-octadecenoyl-CoA + H2O2
show the reaction diagram
trans-3-decenoyl-CoA + O2
?
show the reaction diagram
-
-
-
-
?
trans-3-hexenoyl-CoA + O2
?
show the reaction diagram
-
-
-
-
?
trans-3-octenoyl-CoA + O2
?
show the reaction diagram
-
-
-
-
?
trihydroxycholestanoyl-CoA + O2
trans-2,3-dehydrotrihydroxycholestanoyl-CoA + H2O2
show the reaction diagram
-
-
-
?
trihydroxycoprostanoyl-CoA + O2
?
show the reaction diagram
-
-
-
-
?
additional information
?
-