1.3.7.1: 6-hydroxynicotinate reductase

This is an abbreviated version!
For detailed information about 6-hydroxynicotinate reductase, go to the full flat file.

Reaction

Synonyms

6-hydroxynicotinic reductase, 6-oxotetrahydronicotinate dehydrogenase, HNA reductase, reductase, 6-hydroxynicotinate

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.7 With an iron-sulfur protein as acceptor

                1.3.7.1 6-hydroxynicotinate reductase

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in table

3

Activating Compound

96

AA Sequence

1

CAS Registry Number

2

Cofactor

5

General Stability

2

KM Value [mM]

1

Metals/Ions

1

Molecular Weight [Da]

1

Natural Substrates/ Products (Substrates)

3

Organism

1

Oxidation Stability

3

Pathway

1

pH Optimum

1

pH Range

1

pH Stability

2

Purification (Commentary)

1

Reaction

3

Reaction Type

3

Reference

2

Specific Activity [micromol/min/mg]

1

Storage Stability

6

Substrates and Products (Substrate)

1

Subunits

4

Synonyms

1

Systematic Name

1

Temperature Optimum [°C]

1

Temperature Stability [°C]

pH Range

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pH Range on EC 1.3.7.1 - 6-hydroxynicotinate reductase

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pH RANGE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

5.5 - 8.2

Clostridium sp.

-

pH 5.5: about 60% of activity maximum, pH 8.2: about 20% of activity maximum, rapid decline in activity below pH 5.6 may be partly due to destruction of ferredoxin in acid

391150