1.3.8.12: (2S)-methylsuccinyl-CoA dehydrogenase

This is an abbreviated version!
For detailed information about (2S)-methylsuccinyl-CoA dehydrogenase, go to the full flat file.

Reaction

Synonyms

MCD, methylsuccinyl-CoA dehydrogenase, PdMCD

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.8 With a flavin as acceptor

                1.3.8.12 (2S)-methylsuccinyl-CoA dehydrogenase

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Results	in table
124	AA Sequence
4	Cloned(Commentary)
6	Cofactor
2	Crystallization (Commentary)
12	General Information
10	kcat/KM [mM/s]
11	KM Value [mM]
2	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
4	Organism
6	Pathway
3	pH Optimum
28	Protein Variants
4	Purification (Commentary)
1	Reaction
4	Reference
1	Source Tissue
15	Substrates and Products (Substrate)
5	Subunits
8	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
10	Turnover Number [1/s]

KCat KM Value

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KCat KM Value on EC 1.3.8.12 - (2S)-methylsuccinyl-CoA dehydrogenase

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kcat/KM VALUE [1/mMs^-1]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

1.6 - 1028.75

(2S)-methylsuccinyl-CoA

6 entries

2.27 - 5.3

succinyl-CoA

4 entries

1.6

(2S)-methylsuccinyl-CoA

Paracoccus denitrificans

A1B5Y0

mutant enzyme A282F/F284A, at pH 7.5 and 30°C

763257

1.62

(2S)-methylsuccinyl-CoA

Paracoccus denitrificans

A1B5Y0

recombinant mutant A282F/F284A, pH 7.5, 30°C

763257

496.9

(2S)-methylsuccinyl-CoA

Paracoccus denitrificans

A1B5Y0

recombinant mutant A282V, pH 7.5, 30°C

763257

500

(2S)-methylsuccinyl-CoA

Paracoccus denitrificans

A1B5Y0

mutant enzyme A282V, at pH 7.5 and 30°C

763257

1000

(2S)-methylsuccinyl-CoA

Paracoccus denitrificans

A1B5Y0

wild type enzyme, at pH 7.5 and 30°C

763257

1028.75

(2S)-methylsuccinyl-CoA

Paracoccus denitrificans

A1B5Y0

recombinant wild-type enzyme, pH 7.5, 30°C

763257

2.27

succinyl-CoA

Paracoccus denitrificans

A1B5Y0

recombinant wild-type enzyme, pH 7.5, 30°C

763257

2.3

succinyl-CoA

Paracoccus denitrificans

A1B5Y0

wild type enzyme, at pH 7.5 and 30°C

763257

5.26

succinyl-CoA

Paracoccus denitrificans

A1B5Y0

recombinant mutant A282V, pH 7.5, 30°C

763257

5.3

succinyl-CoA

Paracoccus denitrificans

A1B5Y0

mutant enzyme A282V, at pH 7.5 and 30°C

763257