1.3.8.3: (R)-benzylsuccinyl-CoA dehydrogenase

This is an abbreviated version!
For detailed information about (R)-benzylsuccinyl-CoA dehydrogenase, go to the full flat file.

Reaction

Synonyms

bbgS, BbsG, EC 1.3.99.21

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.8 With a flavin as acceptor

                1.3.8.3 (R)-benzylsuccinyl-CoA dehydrogenase

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in table

880

AA Sequence

1

CAS Registry Number

4

Cloned(Commentary)

11

Cofactor

2

General Information

1

Inhibitors

3

KM Value [mM]

2

Molecular Weight [Da]

12

Natural Substrates/ Products (Substrates)

19

Organism

6

Pathway

3

pH Optimum

1

Purification (Commentary)

1

Reaction

3

Reaction Type

17

Reference

3

Specific Activity [micromol/min/mg]

15

Substrates and Products (Substrate)

6

Subunits

20

Synonyms

1

Systematic Name

3

Temperature Optimum [°C]

Systematic Name

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Systematic Name on EC 1.3.8.3 - (R)-benzylsuccinyl-CoA dehydrogenase

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SYSTEMATIC NAME

IUBMB Comments

(R)-benzylsuccinyl-CoA:electron transfer flavoprotein oxidoreductase

Requires FAD as prosthetic group. Unlike other acyl-CoA dehydrogenases, this enzyme exhibits high substrate- and enantiomer specificity; it is highly specific for (R)-benzylsuccinyl-CoA and is inhibited by (S)-benzylsuccinyl-CoA. Forms the third step in the anaerobic toluene metabolic pathway in Thauera aromatica. Ferricenium ion is an effective artificial electron acceptor.