1.3.98.4: 5a,11a-dehydrotetracycline reductase
This is an abbreviated version!
For detailed information about 5a,11a-dehydrotetracycline reductase, go to the full flat file.
Reaction
Synonyms
12-dehydrotetracycline dehydrogenase, 12-dehydrotetracycline reductase, dehydrooxytetracycline dehydrogenase, oxyR
ECTree
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Cofactor
Cofactor on EC 1.3.98.4 - 5a,11a-dehydrotetracycline reductase
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7,8-didemethyl-8-hydroxy-5-deazariboflavin
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i.e. cosynthetic facor-1
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cosynthetic factor-1 enables Streptomyces aureofaciens to produce tetracycline instead of their 5a,11a-dehydro analogues
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additional information
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isolation of Cosynthetic Factor I, required for catayltic activity. The factor is dialysable and stable to autoclaving over the pH range of 1 to 10
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