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1.3.98.7: [mycofactocin precursor peptide]-tyrosine decarboxylase

This is an abbreviated version!
For detailed information about [mycofactocin precursor peptide]-tyrosine decarboxylase, go to the full flat file.

Reaction

C-terminal [mycofactocin precursor peptide]-glycyl-L-valyl-L-tyrosine
+
S-adenosyl-L-methionine
=
C-terminal [mycofactocin precursor peptide]-glycyl-L-valyl-4-[2-aminoethenyl]phenol
+
CO2
+
5'-deoxyadenosine
+
L-methionine

Synonyms

mftC, MtfC, mycofactocin maturase, Rv0693

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.98 With other, known, physiological acceptors
                1.3.98.7 [mycofactocin precursor peptide]-tyrosine decarboxylase

Systematic Name

Systematic Name on EC 1.3.98.7 - [mycofactocin precursor peptide]-tyrosine decarboxylase

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SYSTEMATIC NAME
IUBMB Comments
C-terminal [mycofactocin precursor peptide]-glycyl-L-valyl-L-tyrosine L-tyrosine-carboxylyase
This is a bifunctional radical AdoMet (radical SAM) enzyme that catalyses the first two steps in the biosynthesis of the enzyme cofactor mycofactocin. Activity requires the presence of the MftB chaperone. The other activity of the enzyme is EC 4.1.99.26, 3-amino-5-[(4-hydroxyphenyl)methyl]-4,4-dimethylpyrrolidin-2-one synthase.