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1.3.99.23: all-trans-retinol 13,14-reductase

This is an abbreviated version!
For detailed information about all-trans-retinol 13,14-reductase, go to the full flat file.

Word Map on EC 1.3.99.23

Reaction

all-trans-13,14-dihydroretinol
+
acceptor
=
all-trans-retinol
 +
reduced acceptor

Synonyms

(13,14)-all-trans-retinol saturase, 13,14-dihydroretinol saturase, all-trans-13,14-dihydroretinol saturase, all-trans-retinol:all-trans-13,14-dihydroretinol saturase, rat mammary tumor 7, retinol saturase, RetSat, RetSat A, Rmt7

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.99 With unknown physiological acceptors
                1.3.99.23 all-trans-retinol 13,14-reductase

Cloned

Cloned on EC 1.3.99.23 - all-trans-retinol 13,14-reductase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
expressed in NIH-3T3 cells and HEK-293 cells
expressed in T-REx-293 cells
into the Xho I site of pCDNA4/TO and expressed in T-REx-293 cells, cloned into the vector pCRII-TOPO
quantitative real-time PCR expression analysis
-
the cDNA for the mouse enzyme is cloned from reverse transcribed RNA of retina and retinal pigment endothelium and used to establish human embryonic kidney (HEK-293) cells with or without ectopic protein expression