1.3.99.23: all-trans-retinol 13,14-reductase

This is an abbreviated version!
For detailed information about all-trans-retinol 13,14-reductase, go to the full flat file.

Reaction

Synonyms

(13,14)-all-trans-retinol saturase, 13,14-dihydroretinol saturase, all-trans-13,14-dihydroretinol saturase, all-trans-retinol:all-trans-13,14-dihydroretinol saturase, rat mammary tumor 7, retinol saturase, RetSat, RetSat A, Rmt7

ECTree

     1 Oxidoreductases

         1.3 Acting on the CH-CH group of donors

             1.3.99 With unknown physiological acceptors

                1.3.99.23 all-trans-retinol 13,14-reductase

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Results

in table

4

Activating Compound

111

AA Sequence

6

Application

1

CAS Registry Number

8

Cloned(Commentary)

25

Cofactor

31

Disease/ Diagnostics

8

Engineering

10

Expression

20

General Information

1

Inhibitors

9

Localization

3

Molecular Weight [Da]

28

Natural Substrates/ Products (Substrates)

18

Organism

1

Pathway

1

Reaction

9

Reaction Type

17

Reference

47

Source Tissue

42

Substrates and Products (Substrate)

39

Synonyms

1

Systematic Name

Natural Substrates Products

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Natural Substrates Products on EC 1.3.99.23 - all-trans-retinol 13,14-reductase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

(R)-all-trans-13,14-dihydroretinol + acceptor

all-trans-retinol + reduced acceptor

Mus musculus

-

retinol saturase catalyzes the saturation of all-trans-retinol to produce (R)-all-trans-13,14-dihydroretinol

711959

-

-

r

10'-apo-beta-carotene-3,10'-diol + acceptor

11',12'-dihydro-10'-apo-beta-carotene-3,10'-diol + reduced acceptor

Danio rerio

Q5BLE8

i.e. galloxanthin

763769

-

-

?

all-trans-13,14-dihydroretinol + acceptor

all-trans-retinol + reduced acceptor

Mus musculus

-

-

725598

-

-

?

all-trans-13,14-dihydroretinol + FAD

all-trans-retinol + FADH2

6 entries

all-trans-13,14-dihydroretinol + NAD+

all-trans-retinol + NADH + H+

6 entries

all-trans-13,14-dihydroretinol + NADP+

all-trans-retinol + NADPH + H+

6 entries

all-trans-retinol + reduced acceptor

all-trans-13,14-dihydroretinol + acceptor

4 entries

all-trans-13,14-dihydroretinol + FAD

all-trans-retinol + FADH2

Danio rerio

Q5BLE8

-

763769

-

-

?

all-trans-13,14-dihydroretinol + FAD

all-trans-retinol + FADH2

Homo sapiens

Q6NUM9

-

763507, 763769

-

-

?

all-trans-13,14-dihydroretinol + FAD

all-trans-retinol + FADH2

Homo sapiens

-

-

763769

-

-

?

all-trans-13,14-dihydroretinol + FAD

all-trans-retinol + FADH2

Mus musculus

Q64FW2

-

763507, 763769

-

-

?

all-trans-13,14-dihydroretinol + FAD

all-trans-retinol + FADH2

Mus musculus C57BL/6J

Q64FW2

-

763507

-

-

?

all-trans-13,14-dihydroretinol + FAD

all-trans-retinol + FADH2

Rattus norvegicus

Q8VHE9

-

763769

-

-

?

all-trans-13,14-dihydroretinol + NAD+

all-trans-retinol + NADH + H+

Danio rerio

Q5BLE8

-

763769

-

-

?

all-trans-13,14-dihydroretinol + NAD+

all-trans-retinol + NADH + H+

Homo sapiens

Q6NUM9

-

763507, 763769

-

-

?

all-trans-13,14-dihydroretinol + NAD+

all-trans-retinol + NADH + H+

Homo sapiens

-

-

763769

-

-

?

all-trans-13,14-dihydroretinol + NAD+

all-trans-retinol + NADH + H+

Mus musculus

Q64FW2

-

763507, 763769

-

-

?

all-trans-13,14-dihydroretinol + NAD+

all-trans-retinol + NADH + H+

Mus musculus C57BL/6J

Q64FW2

-

763507

-

-

?

all-trans-13,14-dihydroretinol + NAD+

all-trans-retinol + NADH + H+

Rattus norvegicus

Q8VHE9

-

763769

-

-

?

all-trans-13,14-dihydroretinol + NADP+

all-trans-retinol + NADPH + H+

Danio rerio

Q5BLE8

-

763769

-

-

?

all-trans-13,14-dihydroretinol + NADP+

all-trans-retinol + NADPH + H+

Homo sapiens

Q6NUM9

-

763507, 763769

-

-

?

all-trans-13,14-dihydroretinol + NADP+

all-trans-retinol + NADPH + H+

Homo sapiens

-

-

763769

-

-

?

all-trans-13,14-dihydroretinol + NADP+

all-trans-retinol + NADPH + H+

Mus musculus

Q64FW2

-

763507, 763769

-

-

?

all-trans-13,14-dihydroretinol + NADP+

all-trans-retinol + NADPH + H+

Mus musculus C57BL/6J

Q64FW2

-

763507

-

-

?

all-trans-13,14-dihydroretinol + NADP+

all-trans-retinol + NADPH + H+

Rattus norvegicus

Q8VHE9

-

763769

-

-

?

all-trans-retinol + reduced acceptor

all-trans-13,14-dihydroretinol + acceptor

Homo sapiens

-

-

700994

-

-

?

all-trans-retinol + reduced acceptor

all-trans-13,14-dihydroretinol + acceptor

Homo sapiens

-

-

700301

-

-

ir

all-trans-retinol + reduced acceptor

all-trans-13,14-dihydroretinol + acceptor

Mus musculus

-

-

700994

-

-

?

all-trans-retinol + reduced acceptor

all-trans-13,14-dihydroretinol + acceptor

Mus musculus

Q64FW2

-

659418

-

-

?