1.3.99.24: 2-amino-4-deoxychorismate dehydrogenase

This is an abbreviated version!
For detailed information about 2-amino-4-deoxychorismate dehydrogenase, go to the full flat file.

Reaction

(2S)-2-amino-4-deoxychorismate
+
FMN
=
3-(1-carboxyvinyloxy)anthranilate
+
FMNH2

Synonyms

ADIC dehydrogenase, SgcG

ECTree

     1 Oxidoreductases
         1.3 Acting on the CH-CH group of donors
             1.3.99 With unknown physiological acceptors
                1.3.99.24 2-amino-4-deoxychorismate dehydrogenase

Natural Substrates Products

Natural Substrates Products on EC 1.3.99.24 - 2-amino-4-deoxychorismate dehydrogenase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
2-amino-2-deoxyisochorismate + FMN
3-enolpyruvoylanthranilate + FMNH2
show the reaction diagram
-
the sequential action of 2-amino-4-deoxychorismate synthase (EC 2.6.1.86) and EC 1.3.99.24 leads to the formation of the benzoxazolinate moiety of the enediyne antitumour antibiotic C-1027
-
-
?