220.127.116.11: 2-furoyl-CoA dehydrogenase
This is an abbreviated version, for detailed information about 2-furoyl-CoA dehydrogenase, go to the full flat file.
2-furoyl coenzyme A dehydrogenase, 2-furoyl coenzyme A hydroxylase, dehydrogenase, 2-furoyl coenzyme A, furoyl-CoA hydroxylase
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Systematic Name on EC 18.104.22.168 - 2-furoyl-CoA dehydrogenase
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2-furoyl-CoA:acceptor 5-oxidoreductase (hydroxylating)
A copper protein. The oxygen atom of the -OH produced is derived from water, not O2; the actual oxidative step is probably dehydrogenation of a hydrated form -CHOH-CH2- to -C(OH)=CH-, which tautomerizes non-enzymically to -CO-CH2-, giving (5-oxo-4,5-dihydro-2-furoyl)-CoA. Methylene blue, nitro blue, tetrazolium and a membrane fraction from Pseudomonas putida can act as acceptors.