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1.4.1.10: glycine dehydrogenase

This is an abbreviated version!
For detailed information about glycine dehydrogenase, go to the full flat file.

Word Map on EC 1.4.1.10

Reaction

glycine
+
H2O
+
NAD+
=
glyoxylate
+
NH3
+
NADH
+
H+

Synonyms

dehydrogenase, glycine

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.1 With NAD+ or NADP+ as acceptor
                1.4.1.10 glycine dehydrogenase

Disease

Disease on EC 1.4.1.10 - glycine dehydrogenase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Hyperglycinemia, Nonketotic
Epigenetic Silencing of the Putative Tumor Suppressor Gene GLDC (Glycine Dehydrogenase) in Gastric Carcinoma.
Lung Neoplasms
Serum glycine dehydrogenase is associated with increased risk of lung cancer and promotes malignant transformation by regulating DNA methyltransferases expression.
Neoplasms
Epigenetic Silencing of the Putative Tumor Suppressor Gene GLDC (Glycine Dehydrogenase) in Gastric Carcinoma.
Obesity
Obesity increases hepatic glycine dehydrogenase and aminomethyltransferase expression while dietary glycine supplementation reduces white adipose tissue in Zucker diabetic fatty rats.
Tuberculosis
ald of Mycobacterium tuberculosis encodes both the alanine dehydrogenase and the putative glycine dehydrogenase.
Dormancy of Mycobacterium tuberculosis and latency of disease.
Glycine and alanine dehydrogenase activities are catalyzed by the same protein in Mycobacterium smegmatis: upregulation of both activities under microaerophilic adaptation.
Identification of genes required for chronic persistence of Brucella abortus in mice.