1.4.1.11: L-erythro-3,5-diaminohexanoate dehydrogenase

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For detailed information about L-erythro-3,5-diaminohexanoate dehydrogenase, go to the full flat file.

Reaction

Synonyms

dehydrogenase, L-3,5-diaminohexanoate, L-3,5-diaminohexanoate dehydrogenase, L-erythro-3,5-diaminohexanoate dehydrogenase

ECTree

     1 Oxidoreductases

         1.4 Acting on the CH-NH₂ group of donors

             1.4.1 With NAD⁺ or NADP⁺ as acceptor

                1.4.1.11 L-erythro-3,5-diaminohexanoate dehydrogenase

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Results	in table
153	AA Sequence
1	CAS Registry Number
4	Cofactor
1	General Stability
4	Inhibitors
4	Ki Value [mM]
10	KM Value [mM]
5	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
14	Organism
5	Pathway
18	PDB ID
1	pH Optimum
1	pH Range
3	pH Stability
2	Purification (Commentary)
1	Reaction
5	Reaction Type
3	Reference
1	Specific Activity [micromol/min/mg]
3	Storage Stability
6	Substrates and Products (Substrate)
6	Subunits
4	Synonyms
1	Systematic Name
1	Temperature Stability [°C]

Substrates Products

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Substrates Products on EC 1.4.1.11 - L-erythro-3,5-diaminohexanoate dehydrogenase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

L-erythro-3,5-diaminohexanoate + H2O + NAD+

5-amino-3-oxohexanoate + NADH + NH4+

2 entries

L-erythro-3,5-diaminohexanoate + H2O + NAD+

5-amino-3-oxohexanoate + NH3 + NADH + H+

4 entries

L-erythro-3,5-diaminohexanoate + H2O + NAD+

5-amino-3-oxohexanoate + NADH + NH4+

Clostridium sp.

-

the equilibrium of the dehydrogenase reaction is more favorable for amino acid oxidation than are the equilibria of other similar reactions

391434

-

-

r

L-erythro-3,5-diaminohexanoate + H2O + NAD+

5-amino-3-oxohexanoate + NADH + NH4+

Clostridium sp. SB4

-

the equilibrium of the dehydrogenase reaction is more favorable for amino acid oxidation than are the equilibria of other similar reactions

391434

-

-

r

L-erythro-3,5-diaminohexanoate + H2O + NAD+

5-amino-3-oxohexanoate + NH3 + NADH + H+

Brevibacterium L5

-

3-keto-5-aminohexanoate has the (5S) configuration. First step in the decomposition of 3,5-diaminohexanoate by the aerobic Brevibacterium L5

391432

-

-

r

L-erythro-3,5-diaminohexanoate + H2O + NAD+

5-amino-3-oxohexanoate + NH3 + NADH + H+

Brevibacterium L5

-

3-keto-5-aminohexanoate has the (5S) configuration

391432

-

-

r

L-erythro-3,5-diaminohexanoate + H2O + NAD+

5-amino-3-oxohexanoate + NH3 + NADH + H+

Clostridium sp.

-

enzyme is involved in lysine degradation

391434

-

-

?

L-erythro-3,5-diaminohexanoate + H2O + NAD+

5-amino-3-oxohexanoate + NH3 + NADH + H+

Clostridium sp. SB4

-

enzyme is involved in lysine degradation

391434

-

-

?