1.4.1.12: 2,4-diaminopentanoate dehydrogenase

This is an abbreviated version!
For detailed information about 2,4-diaminopentanoate dehydrogenase, go to the full flat file.

Word Map on EC 1.4.1.12

Reaction

(2R,4S)-2,4-diaminopentanoate
+
H2O
+
NAD(P)+
=
(2R)-2-amino-4-oxopentanoate
+
NH3
+
NAD(P)H
+
H+

Synonyms

2,4-DAPDH, 2,4-diaminopentanoic acid C4 dehydrogenase, 2R,4S-2,4-diaminopentanoate dehydrogenase, DAPDH

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.1 With NAD+ or NADP+ as acceptor
                1.4.1.12 2,4-diaminopentanoate dehydrogenase

Reference

Reference on EC 1.4.1.12 - 2,4-diaminopentanoate dehydrogenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Somack, R.; Costilow, R.N.
2,4-Diaminopentanoic acid C4 dehydrogenase, purification and properties of the protein
J. Biol. Chem.
247
385-388
1973
Acetoanaerobium sticklandii
Manually annotated by BRENDA team
Stadtman, T.C.
Lysine metyabolim by clostridia, XIIB 2,5-diaminohexanoate dehydrogenase (2,4-diaminopentanoate dehydrogenase)
Adv. Enzymol. Relat. Areas Mol. Biol.
38
441-445
1973
Clostridium sp., Acetoanaerobium sticklandii, Clostridium sp. M-E SB4
-
Manually annotated by BRENDA team
Tsuda, Y.; Friedmann, H.C.
Ornithine metabolism by Clostridium sticklandii. Oxidation of ornithine to 2-amino-4-ketopentanoic acid via 2,4-diaminopentanoic acid; participation of B12 coenzyme, pyridoxal phosphate, and pyridine nucleotide
J. Biol. Chem.
245
5914-5926
1970
Acetoanaerobium sticklandii
Manually annotated by BRENDA team
Fonknechten, N.; Perret, A.; Perchat, N.; Tricot, S.; Lechaplais, C.; Vallenet, D.; Vergne, C.; Zaparucha, A.; Le Paslier, D.; Weissenbach, J.; Salanoubat, M.
A conserved gene cluster rules anaerobic oxidative degradation of L-ornithine
J. Bacteriol.
191
3162-3167
2009
Acetoanaerobium sticklandii
Manually annotated by BRENDA team
Fukuyama, S.; Mihara, H.; Miyake, R.; Ueda, M.; Esaki, N.; Kurihara, T.
Characterization of a thermostable 2,4-diaminopentanoate dehydrogenase from Fervidobacterium nodosum Rt17-B1
J. Biosci. Bioeng.
117
551-556
2014
Fervidobacterium nodosum
Manually annotated by BRENDA team