1.4.1.14: glutamate synthase (NADH)
This is an abbreviated version!
For detailed information about glutamate synthase (NADH), go to the full flat file.
Word Map on EC 1.4.1.14
Reaction
2 L-glutamate
+
Synonyms
gltA, GltA2, gltB, glutamate (reduced nicotinamide adenine dinucleotide) synthase, glutamate synthase, glutamate synthase (NADH), glutamate synthase (NADH-dependent), glutamate synthetase, glutamine 2-oxoglutarate aminotransferase, GOGAT, GOGAT1, GOGAT2, L-glutamate synthase (NADH), L-glutamate synthetase, NADH glutamate synthase, NADH-dependent glutamate synthase, NADH-dependent glutamine-2-oxoglutarate aminotransferase, NADH-GltS, NADH-glutamate synthase, NADH-GOGAT, NADH-GOGAT I, NADH-GOGAT II, NADH-GOGAT1, NADH-GOGAT2, NADH: GOGAT, Os01g0681900, Os05g0555600, synthase, glutamate (reduced nicotinamide adenine dinucleotide)
ECTree
1.4.1.14 glutamate synthase (NADH)Advanced search results
results (
results (Natural Substrates Products
Natural Substrates Products on EC 1.4.1.14 - glutamate synthase (NADH)
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
additional information
?
-
-
enzyme is important for nitrogen assimilation, reduced enzyme ativity impairs N assimilation, overview
-
-
?
2 L-glutamate + NAD+
L-glutamine + 2-oxoglutarate + NADH + H+
-
-
-
-
r
2 L-glutamate + NAD+
L-glutamine + 2-oxoglutarate + NADH + H+
-
-
-
-
r
2 L-glutamate + NAD+
L-glutamine + 2-oxoglutarate + NADH + H+
-
-
-
r
2 L-glutamate + NAD+
L-glutamine + 2-oxoglutarate + NADH + H+
-
-
-
-
r
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
ammonia assimilation
-
-
?
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
ammonia assimilation
-
-
?
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
regulatory role in biosynthesis pathways involving glutamate, early acceptor of fixed nitrogen
-
?
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
ammonia assimilation
-
?
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
ammonia assimilation from fixed nitrogen, de novo synthesis of glutamate
-
?
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
role in overall ammonia assimilation system, involved in nitrogen metabolism
-
-
ir
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
key enzyme in pathway of assimilation of symbiotically fixed N2 into amino acids
-
?
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
root nodule ammonia assimilation, enzyme plays a central role in the functioning of effective root nodules
-
?
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
predominant enzyme in N2-fixing root nodules and roots, whereas in leaves and cotyledons Fd-GOGAT is the major form of GOGAT involved in nitrogen assimilation, NADH-GOGAT may be a rate-limiting step in NH4+ assimilation in root nodules
-
?
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
key enzyme in pathway of assimilation of symbiotically fixed N2 into amino acids
-
?
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
plays a critical role in the assimilation of symbiotically fixed nitrogen in nodules and during pollen development
-
?
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
important role in glutamine degradation
-
-
?
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
glutamine synthetase/glutamate synthase pathway for ammonia assimilation is fafavoured by growth at low concentrations of ammonia
-
?
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
Neurospora crassa am-1
-
glutamine synthetase/glutamate synthase pathway for ammonia assimilation is fafavoured by growth at low concentrations of ammonia
-
?
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
glutamate biosynthesis
-
?
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
assimilation of exogeneously supplied NH4+ is primarily via the cytosolic glutamine synthetase/plastidial NADH-GOGAT cycle in specific regions of the epidermis and exodermis in roots
one of the two synthezised glutamate molecules can be cycled back as substrate for glutamine synthetase reaction and the other can be used for many synthetic reactions
ir
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
ammonia assimilation
one of the two synthezised glutamate molecules can be cycled back as substrate for glutamine synthetase reaction and the other can be used for many synthetic reactions
ir
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
important role in the generation of glutamate for the assimilation of ammonium ions via the glutamine synthetase reaction in the epidermis and exodermis of the root surface, role in the re-utilization of glutamine transported from phloem and xylem in young leaves and grains at the early stage of ripening of rice plants
one of the two synthezised glutamate molecules can be cycled back as substrate for glutamine synthetase reaction and the other can be used for many synthetic reactions
ir
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
important role in the generation of glutamate for the assimilation of ammonium ions via the glutamine synthetase reaction in the epidermis and exodermis of the root surface, role in the re-utilization of glutamine transported from phloem and xylem in young leaves and grains at the early stage of ripening of rice plants
one of the two synthezised glutamate molecules can be cycled back as substrate for glutamine synthetase reaction and the other can be used for many synthetic reactions
ir
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
role in synthesis of glutamate for growth and development in higher plants
-
-
?
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
enzyme in developing organs, such as unexpanded non-green leaves and developing grains, could be involved in the utilization of remobilized nitrogen
-
?
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
ammonia assimilation
-
?
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
glutamine synthetase/glutamate synthase pathway for ammonia assimilation is fafavoured by growth at low concentrations of ammonia
-
ir
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
key enzyme for glutamate production
-
ir
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
glutamine synthetase/glutamate synthase pathway for ammonia assimilation is fafavoured by growth at low concentrations of ammonia
-
ir
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
key enzyme for glutamate production
-
ir
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
glutamate biosynthesis
-
ir
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
glutamate biosynthesis
-
ir
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
involvement in glutamine metabolism, when glucose is in excess
-
ir
L-glutamine + 2-oxoglutarate + NADH
glutamate + NAD+
-
involvement in glutamine metabolism, when glucose is in excess
-
ir
L-glutamine + 2-oxoglutarate + NADH + H+
L-glutamate + NAD+
-
-
-
-
?
