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1.4.1.16: diaminopimelate dehydrogenase

This is an abbreviated version!
For detailed information about diaminopimelate dehydrogenase, go to the full flat file.

Word Map on EC 1.4.1.16

Reaction

meso-2,6-diaminoheptanedioate
+
H2O
 +
NADP+
=
L-2-amino-6-oxoheptanedioate
 +
NH3
 +
NADPH
 +
H+

Synonyms

BAB07799, BF3690, DAPDH, DDH, meso-2,6-diaminopimelate dehydrogenase, meso-alpha,epsilon-diaminopimelate dehydrogenase, meso-DAPDH, meso-diaminopimelate dehydrogenase, NADP+-dependent meso-diaminopimelate dehydrogenase, Sth1425, Theth_1310

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.1 With NAD+ or NADP+ as acceptor
                1.4.1.16 diaminopimelate dehydrogenase

Substrates Products

Substrates Products on EC 1.4.1.16 - diaminopimelate dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(S)-2-amino-6-oxoheptanedioate + H+ + NADH + NH4+
meso-2,6-diaminoheptanedioate + H2O + NAD+
show the reaction diagram
(S)-2-amino-6-oxoheptanedioate + H+ + NADPH + NH4+
meso-2,6-diaminoheptanedioate + H2O + NADP+
show the reaction diagram
2,6-diaminoheptanedioic acid + H2O + NADP+
2-amino-6-oxopimelate + NH3 + NADPH
show the reaction diagram
-
mixture of all possible stereoisomers, 4% of activity with meso-2,6-diaminopimelate
-
r
2-amino-6-(hydroxyamino)heptanedioic acid + H2O + NADP+
2-hydroxyamino-6-oxopimelate + NH3 + NADPH
show the reaction diagram
-
mixture of all possible stereoisomers, 22% of activity with meso-2,6-diaminopimelate
-
r
2-oxo(phenyl)acetate + NH3 + NADPH + H+
(2S)-amino(phenyl)acetate + NADP+
show the reaction diagram
-
-
-
r
2-oxo-3,3-dimethylbutanoate + NH3 + NADPH + H+
(2S)-2-amino-3,3-dimethylbutanoate + NADP+
show the reaction diagram
-
-
-
r
2-oxo-3-methylbutanoate + NH3 + NADPH + H+
(2S)-2-amino-3-methylbutanoate + NADP+
show the reaction diagram
-
-
-
r
2-oxo-3-phenylpropanoate + NH3 + NADPH + H+
(2S)-2-amino-3-phenylpropanoate + NADP+
show the reaction diagram
-
-
-
r
2-oxo-4-methylpentanoate + NH3 + NADPH + H+
(2S)-2-amino-4-methylpentanoate + NADP+
show the reaction diagram
-
-
-
r
2-oxo-4-phenylbutanoate + NH3 + NADPH + H+
(2S)-2-amino-4-phenylbutanoate + NADP+
show the reaction diagram
-
-
-
r
2-oxobutanoate + NH3 + NADPH + H+
(2S)-2-aminobutanoate + NADP+
show the reaction diagram
-
-
-
r
2-oxobutanoate + NH3 + NADPH + H+
D-2-aminobutanoate + NADP+
show the reaction diagram
2-oxoglutarate + NH3 + NADPH + H+
D-glutamate + NADP+
show the reaction diagram
2-oxooctanoate + NH3 + NADPH + H+
D-2-aminooctanoate + NADP+
show the reaction diagram
2-oxopentanoate + NH3 + NADPH + H+
(2S)-2-aminopentanoate + NADP+
show the reaction diagram
-
-
-
r
2-oxosuccinic acid + NH3 + NADPH + H+
?
show the reaction diagram
2-oxovalerate + NH3 + NADPH + H+
? + H2O + NADP+
show the reaction diagram
3-(1H-indol-3-yl)-2-oxopropanoate + NH3 + NADPH + H+
(2S)-2-amino-3-(1H-indol-3-yl)propanoate + NADP+
show the reaction diagram
-
-
-
r
3-methyl-2-oxobutanoate + NH3 + NADPH + H+
?
show the reaction diagram
3-methyl-2-oxobutanoate + NH3 + NADPH + H+
? + H2O + NADP+
show the reaction diagram
3-methyl-2-oxobutanoate + NH3 + NADPH + H+
D-valine + NADP+
show the reaction diagram
-
-
-
?
3-methyl-2-oxopentanoic acid + NH3 + NADPH + H+
D-isoleucine + NADP+
show the reaction diagram
-
-
-
?
4-methyl-2-oxopentanoate + NH3 + NADPH + H+
? + H2O + NADP+
show the reaction diagram
4-methyl-2-oxopentanoate + NH3 + NADPH + H+
D-leucine + NADP+
show the reaction diagram
-
-
-
?
4-methyl-2-oxopentanoic acid + NH3 + NADPH + H+
?
show the reaction diagram
4-methylene diaminopimelate + H2O + NADP+
4-methyleneamino-6-oxopimelate + NH3 + NADPH
show the reaction diagram
-
mixture of all possible stereoisomers, 4% of activity with meso-2,6-diaminopimelate
-
r
4-methylthio-2-oxobutanoate + NH3 + NADPH + H+
D-methionine + NADP+
show the reaction diagram
-
-
-
?
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
show the reaction diagram
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
meso-2,6-diaminoheptanedioate + H2O + NADP+
show the reaction diagram
L-DELTA1-tetrahydrodipicolinate + NH4+ + NADPH
meso-2,6-diaminoheptanedioate + NADP+
show the reaction diagram
meso-2,6-diaminoheptanedioate + H2O + NAD+
L-2-amino-6-oxoheptanedioate + NH3 + NADH + H+
show the reaction diagram
meso-2,6-diaminoheptanedioate + H2O + NADP+
L-2-amino-6-oxoheptanedioate + NH3 + NADPH + H+
show the reaction diagram
meso-2,6-diaminoheptanedioate + NADP+
L-DELTA1-tetrahydrodipicolinate + NH4+ + NADPH
show the reaction diagram
oxaloacetate + NH3 + NADPH + H+
? + H2O + NADP+
show the reaction diagram
oxaloacetate + NH3 + NADPH + H+
D-aspartate + NADP+
show the reaction diagram
-
-
-
?
phenylpyruvate + NH3 + NADPH + H+
phenylalanine + NADP+
show the reaction diagram
-
-
-
?
pyruvate + NADPH
?
show the reaction diagram
pyruvate + NH3 + NADPH + H+
D-alanine + H2O + NADP+
show the reaction diagram
pyruvate + NH3 + NADPH + H+
D-alanine + NADP+
show the reaction diagram
additional information
?
-