Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.4.1.18: lysine 6-dehydrogenase

This is an abbreviated version!
For detailed information about lysine 6-dehydrogenase, go to the full flat file.

Word Map on EC 1.4.1.18

Reaction

L-lysine
+
NAD+
+
H2O
=
(S)-2-amino-6-oxohexanoate
+
NADH
+
H+
+
NH3

Synonyms

L-lysine 6-dehydrogenase, L-lysine 6-dehydrogenase (deaminating), L-lysine epsilon-dehydrogenase, Lys 6-DH, LysDH, lysine 6-dehydrogenase

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.1 With NAD+ or NADP+ as acceptor
                1.4.1.18 lysine 6-dehydrogenase

Systematic Name

Systematic Name on EC 1.4.1.18 - lysine 6-dehydrogenase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SYSTEMATIC NAME
IUBMB Comments
L-lysine:NAD+ 6-oxidoreductase (deaminating)
The enzyme is highly specific for L-lysine as substrate, although S-(2-aminoethyl)-L-cysteine can act as a substrate, but more slowly. While the enzyme from Agrobacterium tumefaciens can use only NAD+, that from the thermophilic bacterium Geobacillus stearothermophilus can also use NADP+, but more slowly [1,4].