1.4.1.20: phenylalanine dehydrogenase
This is an abbreviated version!
For detailed information about phenylalanine dehydrogenase, go to the full flat file.
Reaction
Synonyms
dehydrogenase, phenylalanine, L-PheDH, L-phenylalanine dehydrogenase, L-phenylalanine:NAD+ oxidoreductase, deaminating, PDH, PHD, PheDH, phenylalanine dehydrogenase, recombinant PheDH, recombinant phenylalanine dehydrogenase
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Reaction
Reaction on EC 1.4.1.20 - phenylalanine dehydrogenase
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the reductive amination proceeds through a sequential ordered ternary-binary mechanism
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L-phenylalanine + H2O + NAD+ = phenylpyruvate + NH3 + NADH + H+
kinetic mechanism is ordered with NAD+ binding prior to Phe and the products being released in the order of ammonia, phenylpyruvate, and NADH
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L-phenylalanine + H2O + NAD+ = phenylpyruvate + NH3 + NADH + H+
the reductive amination proceeds through a sequential ordered ternary-binary mechanism
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