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1.4.1.21: aspartate dehydrogenase

This is an abbreviated version!
For detailed information about aspartate dehydrogenase, go to the full flat file.

Word Map on EC 1.4.1.21

Reaction

2-iminosuccinate
+
H2O
=
oxaloacetate
+
NH3

Synonyms

AspDH, L-aspartate dehydrogenase, L-aspartate:NAD(P)+ oxidoreductase (deaminating), L-aspDH, NAD-dependent aspartate dehydrogenase, NADH2-dependent aspartate dehydrogenase, NADP+-dependent aspartate dehydrogenase, nadX

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.1 With NAD+ or NADP+ as acceptor
                1.4.1.21 aspartate dehydrogenase

Substrates Products

Substrates Products on EC 1.4.1.21 - aspartate dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-oxoglutarate + NH3 + NAD(P)H + H+
L-glutamate + H2O + NAD(P)+
show the reaction diagram
L-alanine + H2O + NAD(P)+
pyruvate + NH3 + NAD(P)H + H+
show the reaction diagram
L-aspartate + H2O + NAD(P)+
oxaloacetate + NH3 + NAD(P)H + H+
show the reaction diagram
L-aspartate + H2O + NAD+
oxaloacetate + NH3 + NADH + H+
show the reaction diagram
L-aspartate + H2O + NADP+
oxaloacetate + NH3 + NADPH + H+
show the reaction diagram
L-aspartate + NAD(P)+
oxaloacetate + NH4+ + NAD(P)H
show the reaction diagram
L-aspartate + NAD(P)+ + H2O
oxaloacetate + NH4+ + NAD(P)H
show the reaction diagram
-
the enzyme shows pro-R (A-type) stereospecificity for hydrogen transfer from the C4 position of the nicotinamide moiety ofNADH
-
-
?
L-aspartate + NAD+
oxaloacetate + NH4+ + NADH
show the reaction diagram
L-aspartate + NADP+ + H2O
oxaloacetate + NH4+ + NADPH
show the reaction diagram
-
-
-
?
L-glutamate + H2O + NAD(P)+
2-oxoglutarate + NH3 + NAD(P)H + H+
show the reaction diagram
oxaloacetate + NAD(P)H + NH4+
L-aspartate + NAD(P)+
show the reaction diagram
-
-
-
?
oxaloacetate + NH3 + NAD(P)H + H+
L-aspartate + H2O + NAD(P)+
show the reaction diagram
oxaloacetate + NH3 + NADH + H+
L-aspartate + H2O + NAD+
show the reaction diagram
oxaloacetate + NH3 + NADPH + H+
L-aspartate + H2O + NADP+
show the reaction diagram
oxaloacetate + NH4+ + NADH
L-aspartate + NAD+ + H2O
show the reaction diagram
pyruvate + NH3 + NAD(P)H + H+
L-alanine + H2O + NAD(P)+
show the reaction diagram
additional information
?
-