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1.4.1.26: 2,4-diaminopentanoate dehydrogenase (NAD+)

This is an abbreviated version!
For detailed information about 2,4-diaminopentanoate dehydrogenase (NAD+), go to the full flat file.

Reaction

(2R,4S)-2,4-diaminopentanoate
+
H2O
+
NAD+
=
(2R)-2-amino-4-oxopentanoate
+
NH3
+
NADH
+
H+

Synonyms

2,4-DAPDH, 2,4-diaminopentanoate dehydrogenase, DAPDH, Fnod_1646

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.1 With NAD+ or NADP+ as acceptor
                1.4.1.26 2,4-diaminopentanoate dehydrogenase (NAD+)

Substrates Products

Substrates Products on EC 1.4.1.26 - 2,4-diaminopentanoate dehydrogenase (NAD+)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2R,4S)-2,4-diaminopentanoate + H2O + NAD+
(2R)-2-amino-4-oxopentanoate + NH3 + NADH + H+
show the reaction diagram
-
-
-
-
?
(2R,4S)-2,4-diaminopentanoate + H2O + NADP+
(2R)-2-amino-4-oxopentanoate + NH3 + NADPH + H+
show the reaction diagram
-
-
-
-
?
2,5-diaminohexanoate + H2O + NAD+
2-amino-5-oxohexanoate + NH3 + NADH + H+
show the reaction diagram
-
90fold less activity with 2,5-diaminohexanoate compared to (2R,4S)-2,4-diaminopentanoate
-
-
?