1.4.1.3: glutamate dehydrogenase [NAD(P)+]

This is an abbreviated version!
For detailed information about glutamate dehydrogenase [NAD(P)+], go to the full flat file.

Reaction

Synonyms

At5g07440, At5g18170, dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate)), dual-coenzyme specific glutamate dehydrogenase, GDH, gdh-1, GDH1, GDH2, GDH3, GdhA, gdhA_1, GDHB, GDHII, GLDH, GLUD1, GLUD2, GluDH, glutamate dehydrogenase, glutamate dehydrogenase 1, glutamate dehydrogenase 2, glutamic acid dehydrogenase, glutamic dehydrogenase, hGDH1, hGDH2, hGLUD1, hGLUD2, housekeeping glutamate dehydrogenase, L-glutamate dehydrogenase, L-glutamic acid dehydrogenase, Legdh1, Membrane protein 50, MP50, NAD(P)+-dependent glutamate dehydrogenase, NAD(P)-dependent GDH, NAD(P)-dependent glutamate dehydrogenase, NAD(P)-glutamate dehydrogenase, NAD(P)H-dependent glutamate dehydrogenase, NAD(P)H-utilizing glutamate dehydrogenase, NADH-GDH, NADH-glutamate dehydrogenase, TTC1211, TTC1212, TtGDH

ECTree

1 Oxidoreductases

1.4 Acting on the CH-NH₂ group of donors

1.4.1 With NAD⁺ or NADP⁺ as acceptor

1.4.1.3 glutamate dehydrogenase [NAD(P)+]

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Results	in table
91	Activating Compound
1957	AA Sequence
6	Application
1	CAS Registry Number
38	Cloned(Commentary)
184	Cofactor
23	Crystallization (Commentary)
54	Disease/ Diagnostics
1	Expression
36	General Information
13	General Stability
71	IC50 Value
153	Inhibitors
63	Ki Value [mM]
445	KM Value [mM]
42	Localization
7	Metals/Ions
76	Molecular Weight [Da]
30	Natural Substrates/ Products (Substrates)
3	Organic Solvent Stability
185	Organism
11	Pathway
187	PDB ID
73	pH Optimum
12	pH Range
4	pH Stability
2	pI Value
3	Posttranslational Modification
92	Protein Variants
60	Purification (Commentary)
7	Reaction
4	Reaction Type
148	Reference
3	Renatured (Commentary)
139	Source Tissue
67	Specific Activity [micromol/min/mg]
14	Storage Stability
206	Substrates and Products (Substrate)
60	Subunits
118	Synonyms
1	Systematic Name
21	Temperature Optimum [°C]
10	Temperature Range [°C]
49	Temperature Stability [°C]
127	Turnover Number [1/s]

Temperature Range

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Temperature Range on EC 1.4.1.3 - glutamate dehydrogenase [NAD(P)+]

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30 - 90

2 entries

Pyrococcus furiosus

inactive at temperatures below 40°C, undergoes heat activation above 40°C

722592

40 - 90

2 entries

45 - 75

Saccharolobus solfataricus

45°C: about 35% of maximal activity, 75°C: about 20% of maximal activity, substrates: 2-oxoglutarate + NH3 + NADPH

679617

50 - 100

uncultured bacterium

activity range, profile overview. Instability of the coenzyme at temperatures above 95°C

724653

60 - 75

Saccharolobus solfataricus

60°C: about 60% of maximal activity, 75°C: about 30% of maximal activity, substrates: L-glutamate + H2O + NADP+

679617

70 - 100

Pyrococcus horikoshii

70°C: about 35% of maximal activity, 100°C: about 65% of maximal activity, reductive amination of 2-oxoglutarate

654356

80 - 100

Pyrococcus horikoshii

80°C: about 50% of maximal activity, 100°C: about 60% of maximal activity, oxidative amination of ketoglutarate

654356