1.4.1.B2: L-erythro-3,5-diaminohexanoate dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about L-erythro-3,5-diaminohexanoate dehydrogenase (NADP+), go to the full flat file.

Reaction

Synonyms

3,5-DAHDH, Kdd

ECTree

1 Oxidoreductases

1.4 Acting on the CH-NH₂ group of donors

1.4.1 With NAD⁺ or NADP⁺ as acceptor

1.4.1.B2 L-erythro-3,5-diaminohexanoate dehydrogenase (NADP+)

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Results	in table
2	AA Sequence
2	Cloned(Commentary)
7	Cofactor
1	Crystallization (Commentary)
2	General Information
32	Inhibitors
12	Ki Value [mM]
14	KM Value [mM]
4	Metals/Ions
4	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
5	Organism
2	pH Optimum
3	pH Range
1	pH Stability
27	Protein Variants
2	Purification (Commentary)
1	Reaction
5	Reference
1	Specific Activity [micromol/min/mg]
3	Storage Stability
14	Substrates and Products (Substrate)
3	Subunits
2	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]
4	Temperature Stability [°C]

Reference

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Reference on EC 1.4.1.B2 - L-erythro-3,5-diaminohexanoate dehydrogenase (NADP+)

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696177

Baker, J.J.; van der Drift, C.

Purification and properties of L-erythro-3,5-diaminohexanoate dehydrogenase from Clostridium sticklandii

Biochemistry

292-299

1974

Acetoanaerobium sticklandii

4149230

698741

Kreimeyer, A.; Perret, A.; Lechaplais, C.; Vallenet, D.; Medigue, C.; Salanoubat, M.; Weissenbach, J.

Identification of the last unknown genes in the fermentation pathway of lysine

J. Biol. Chem.

282

7191-7197

2007

unidentified (A1X0G6)

17166837

741483

Zhang, D.; Chen, X.; Zhang, R.; Yao, P.; Wu, Q.; Zhu, D.

Development of beta-amino acid dehydrogenase for the synthesis of beta-amino acids via reductive amination of beta-keto acids

ACS Catal.

2220-2224

2015

Candidatus Cloacimonas acidaminovorans

762604

Liu, N.; Wu, L.; Feng, J.; Sheng, X.; Li, J.; Chen, X.; Li, J.; Liu, W.; Zhou, J.; Wu, Q.; Zhu, D.

Crystal structures and catalytic mechanism of L-erythro-3,5-diaminohexanoate dehydrogenase and rational engineering for asymmetric synthesis of beta-amino acids

Angew. Chem. Int. Ed. Engl.

10203-10210

2021

Candidatus Cloacimonas acidaminovorans (B0VJ11), Candidatus Cloacimonas acidaminovorans Evry (B0VJ11)

33624917