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1.4.3.12: cyclohexylamine oxidase

This is an abbreviated version!
For detailed information about cyclohexylamine oxidase, go to the full flat file.

Word Map on EC 1.4.3.12

Reaction

Cyclohexylamine
+
O2
+
H2O
=
cyclohexanone
+
NH3
+
H2O2

Synonyms

ArCHAO, CF596_10820, chaA, CHAO, CHAOCCH12-C2

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.12 cyclohexylamine oxidase

Specific Activity

Specific Activity on EC 1.4.3.12 - cyclohexylamine oxidase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.002
-
substrate: 1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, pH 7.5, 45°C, mutant enzyme W63A
0.006
-
substrate: 1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, pH 7.5, 45°C, mutant enzyme L295Y
0.007
-
substrate: 1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, pH 7.5, 45°C, mutant enzyme L174A
0.009
-
substrate: 1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, pH 7.5, 45°C, mutant enzyme Y433A
0.011
-
substrate: 1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, pH 7.5, 45°C, mutant enzyme Q208A
0.013
-
with 2-ethyl-1-hexylamine as substrate, wild type enzyme, at pH 6.5 and 30°C
0.015
-
substrate: 1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, pH 7.5, 45°C, mutant enzyme F342A
0.016
-
substrate: 1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, pH 7.5, 45°C, mutant enzyme W325A
0.018
-
with (R)-1-(4-chlorophenyl)ethylamine as substrate, wild type enzyme, at pH 6.5 and 30°C
0.053
-
substrate: 1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, pH 7.5, 45°C, mutant enzyme I201A
0.074
-
substrate: 1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, pH 7.5, 45°C, mutant enzyme F317A
0.08
-
with N-methylcyclohexanamine as substrate, wild type enzyme, at pH 6.5 and 30°C
0.084
-
with (R)-1-(4-fluorophenyl)ethanamine as substrate, wild type enzyme, at pH 6.5 and 30°C
0.089
-
substrate: 1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, pH 7.5, 45°C, mutant enzyme T203A
0.09
-
substrate: 1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, pH 7.5, 45°C, mutant enzyme F327A
0.11
-
with 4-methylbenzylamine as substrate, wild type enzyme, at pH 6.5 and 30°C
0.116
-
substrate: 1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, pH 7.5, 45°C, mutant enzyme L200A
0.152
-
substrate: 1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, pH 7.5, 45°C, mutant enzyme L295A
0.166
-
substrate: 1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, pH 7.5, 45°C, mutant enzyme L295I
0.177
-
substrate: 1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, pH 7.5, 45°C, mutant enzyme G202A
0.194
-
substrate: 1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, pH 7.5, 45°C, mutant enzyme I173A
0.26
-
substrate: 1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, pH 7.5, 45°C, wild-type enzyme
0.27
-
with (S)-1-p-tolylethanamine as substrate, wild type enzyme, at pH 6.5 and 30°C
0.33
-
with cyclopentylamine as substrate, wild type enzyme, at pH 6.5 and 30°C
0.34
-
with benzylamine as substrate, wild type enzyme, at pH 6.5 and 30°C
0.461
-
substrate: 1-(4-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline, pH 7.5, 45°C, mutant enzyme P396A
0.68
-
with 2-amino-4-phenylbutane as substrate, wild type enzyme, at pH 6.5 and 30°C
0.97
-
with 2-aminocyclohexanol as substrate, wild type enzyme, at pH 6.5 and 30°C
1.033
-
with cyclooctanamine as substrate, wild type enzyme, at pH 6.5 and 30°C
1.13
-
with 2-aminopentane as substrate, wild type enzyme, at pH 6.5 and 30°C
1.2
-
with 2-aminoheptane as substrate, wild type enzyme, at pH 6.5 and 30°C
1.49
-
with 2-aminonorbornane hydrochloride as substrate, wild type enzyme, at pH 6.5 and 30°C
1.66
-
with (S)-1-phenylpropropan-1-amine as substrate, wild type enzyme, at pH 6.5 and 30°C
2.35
-
with (S)-1-aminoindan as substrate, wild type enzyme, at pH 6.5 and 30°C
2.36
-
with 1-phenylethanamine as substrate, wild type enzyme, at pH 6.5 and 30°C
2.62
-
with (S)-1-(4-chlorophenyl)ethylamine as substrate, wild type enzyme, at pH 6.5 and 30°C
2.79
-
with (S)-2-aminohexane as substrate, wild type enzyme, at pH 6.5 and 30°C
3.058
-
with 2-methylcyclohexanamine as substrate, wild type enzyme, at pH 6.5 and 30°C
3.37
-
with 1-(4-fluorophenyl)ethanamine as substrate, wild type enzyme, at pH 6.5 and 30°C
3.51
-
with (S)-(-)-1-phenylethylamine as substrate, wild type enzyme, at pH 6.5 and 30°C
3.6
-
with 2-amino-5-methylhexane as substrate, wild type enzyme, at pH 6.5 and 30°C
4.56
-
with (S)-1-(4-fluorophenyl)ethanamine as substrate, wild type enzyme, at pH 6.5 and 30°C
5.6
-
with cyclohexylamine as substrate, wild type enzyme, at pH 6.5 and 30°C
5.69
-
with (S)-1-aminotetraline as substrate, wild type enzyme, at pH 6.5 and 30°C