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LOX is highly expressed in early gestational amnion tissue (12-14 weeks)
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highly expressed in vascular lesions
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leg
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mineral-associated fraction
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LOX and LOXL
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LOX and LOXL
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LOX on the surface of pyramidal cells in the grey matter, LOXL in the nuclei of cortex cells and in the cytosol of capillary endothelial cells
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localization of LOX and LOXL in different tissue areas
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mature form of LOXL1 and polymerized LOXL1protein forms
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polymerized LOXL1protein forms
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of lung: LOX and LOXL, renal tubules: only LOXL, intestinal: only LOXL
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of the stomach, mainly LOXL, mucous-secreting cells
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including dermal papillae, follicular sheaths, sebaceous glands
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pyramidal cells: LOXL, not LOX
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epithelial cells, LOXL
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mature form of LOXL1 and polymerized LOXL1protein forms
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LOX and LOXL, of skin epidermis and hair follicles
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determination of LOX activity and expression in donor ocular tissues
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LOX gene expression is reduced in lung cancer cells
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fetal
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in MCF-10A normal breast epithelial cells stably expressing lysyl oxidase LOX has no effect on cell proliferation. Coexpression of lysyl oxidase and placental lactogen leads to a 121% increase in cell proliferation
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polymerized LOXL1protein forms
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LOX mRNA is upregulated in OSCC cells
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LOX gene expression is reduced in pancreatic cancer cells
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apparent lysyl oxidase isozymes contain a highly conserved LOX active site sequence in the nuclei of PC-12 cells
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pepsin-secreting, in the basal part of the stomach, only LOX, no LOXL
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LOXL2, LOX, LOXL
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LOXL
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determination of LOX activity and expression in donor ocular tissues
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localization of LOX and LOXL in different tissue areas
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proliferating cell, LOXL expression, adult tissues
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determination of LOX activity and expression in donor ocular tissues
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smooth muscle cells
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LOX, LOXL, LOXL3, low expression level of LOXL2
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co-localization of LOX and LOXL
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different spatial and temporal expression of LOX and LOXL1 during growth and aging, expression analysis of LOXL1 and LOX in the aorta during the development, growth, and aging of LOU rats, overview
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subluminal stroma surrounding the implanting blastocyst on day 5 of pregnancy
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subluminal stroma surrounding the implanting blastocyst on day 5 of pregnancy
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localization of LOX and LOXL in different tissue areas
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circulating
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lymph node-negative breast adenocarcinoma cell
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hypoxic
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co-localization of LOX and LOXL
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localization of LOX and LOXL in different tissue areas, LOXL is found in the apical surface of columnar absorbing cells, LOX is located in the submucosa
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from days 6 to 8 of pregnancy, the signals for Lox mRNA and protein are strongly detected in the decidual cells
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from days 6 to 8 of pregnancy, the signals for Lox mRNA and protein are strongly detected in the decidual cells
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LOXL-1
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LOXL-1, no expression of LOXL-2
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of skin: LOX and LOXL
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secretion of free soluble enzyme
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secretion of free soluble enzyme
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secretion of free soluble enzyme
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only in fetal heart, LOXL2, very low expression level of LOXL3
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lysyl oxidase protein expression is very scarce in normal hearts, it is highly expressed in failing hearts
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co-localization of LOX and LOXL
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overexpressed in head and neck squamous cell carcinoma compared to normal squamous epithelium
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LOXL4, LOX, LOXL
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localization of LOX and LOXL in different tissue areas
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LOXL-1
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LOXL-1, no expression of LOXL-2
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polymerized LOXL1protein forms
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co-localization of LOX and LOXL
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LOXL4, LOX, LOXL
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co-localization of LOX and LOXL in alveoli and the epithelia of bronchus and bronchiole
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osteoblastic cell, CRL-2593, expression of LOXL1, 3, and 4, not 2, expression patterns during cell differentiatin and matrix mineralization, 4 weeks, overview
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from mantle, fins and arms. Fins show the highest LOX activity
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expression of isozymes during osteoblast differentiation is highly regulated due to their distinct roles in collagen matrix stabilization and subsequent mineralization
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LOXL4, LOX, LOXL
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stromal tissue and ovarian follicle, polycystic ovarian tissue
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localization of LOX and LOXL in different tissue areas
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LOXL4, LOX, LOXL
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LOXL4, LOXL2, LOX, LOXL
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LOXL-1
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LOXL-1, no expression of LOXL-2
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localization of LOX and LOXL in different tissue areas, LOX is located in the inner surface of the pigmented epithelia in the photoreceptor layer, LOXL is located in the inner nuclear layer within the outer plexiform layer and in the ganglion cells
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extract obtained from dill stimulates the LOXL gene expression in dermal equivalents. The stimulation by the dill extract is correlated with increased elastin detection, suggesting an increase in elastogenesis efficiency
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co-localization of LOX and LOXL
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LOXL, lamia propria and straited border, not of Goblet cells
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neural crest- and mesoderm-derived smooth muscle
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nucleus
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LOXL4, LOX, LOXL
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localization of LOX and LOXL in different tissue areas
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LOXL2, LOX, LOXL
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additional information
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not expressed in the embryonic notochord
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additional information
adult fly: LOXL and LOXL-2, the latter occurs exclusively in adult flies, developmental expression analysis of LOX-like proteins LOXL and LOXL2 in embryos, larvae, pupae, and adult flies, no expression of LOXL-2 in larvae, pupae, and embryos, overview
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additional information
adult fly: LOXL and LOXL-2, the latter occurs exclusively in adult flies, developmental expression analysis of LOX-like proteins LOXL and LOXL2 in embryos, larvae, pupae, and adult flies, no expression of LOXL-2 in larvae, pupae, and embryos, overview
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additional information
adult fly: LOXL and LOXL-2, the latter occurs exclusively in adult flies, developmental expression analysis of LOX-like proteins LOXL and LOXL2 in embryos, larvae, pupae, and adult flies, overview
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additional information
adult fly: LOXL and LOXL-2, the latter occurs exclusively in adult flies, developmental expression analysis of LOX-like proteins LOXL and LOXL2 in embryos, larvae, pupae, and adult flies, overview
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additional information
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lysyl oxidase and 4 LOX-like proteins LOXL, LOXL2, LOXL3, and LOXL4 show individual, developmentally regulated tissue and cell-specific expression and localization, expression patterns, LOX and LOXL are expressed in most tissues
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additional information
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no LOXL1 expression in retina
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additional information
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lysyl oxidase and 4 LOX-like proteins LOXL, LOXL2, LOXL3, and LOXL4 show individual, developmentally regulated tissue and cell-specific expression and localization
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additional information
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nearly no enzyme content in blood vessels, expression level of LOX and LOXL in different tissues during development from embryonic, newborn, and young to adult mice, overview
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additional information
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high aortic LOX expression early in the development, i.e. embryonic day 15, followed by a drastic reduction in adulthood, whereas LOXL1 is mainly detectable in the intima and media and is expressed throughout life in the LOU rat
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additional information
quantitative expression analysis of LOX isozymes in different subcellular compartments in PC-12 cells, overview
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