1.4.3.14: L-lysine oxidase

This is an abbreviated version!
For detailed information about L-lysine oxidase, go to the full flat file.

Word Map on EC 1.4.3.14

Reaction

L-lysine
+
O2
+
H2O
=
6-Amino-2-oxohexanoate
+
NH3
+
H2O2

Synonyms

AIP, apoptosis-inducing protein, L-lysine alpha-oxidase, L-lysine-a-oxidase, L-lysine-alpha-oxidase, L-lysyl-alpha-oxidase, L6150, LyOx, lysine-oxidase, LysOx

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.14 L-lysine oxidase

Inhibitors

Inhibitors on EC 1.4.3.14 - L-lysine oxidase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1,4-diaminobutane
1,5-Diaminopentane
-
24% inhibition
1,6-diaminohexane
-
43% inhibition
6-aminocaproic acid
alpha-keto-zeta-aminocaproic acid
-
-
Co2+
-
15% residual activity at 1 mM
Cu2+
-
59% residual activity at 1 mM
L-2,7-diaminoheptanoic acid
-
-
p-chloromercuribenzoate
-
-
Semicarbazide
-
weak competitive, reversible inhibition
additional information
-
EDTA, iodoacetamide and iodoacetate show no substantial effects on the enzyme activity
-