1.4.3.16: L-aspartate oxidase

This is an abbreviated version!
For detailed information about L-aspartate oxidase, go to the full flat file.

Word Map on EC 1.4.3.16

Reaction

L-aspartate
+
O2
=
iminosuccinate
+
H2O2

Synonyms

AO, FIN4, L-Asp oxidase, L-aspartate oxidase, LAO, LASPO, More, nadB, oxidase, L-aspartate, StLASPO

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.16 L-aspartate oxidase

Systematic Name

Systematic Name on EC 1.4.3.16 - L-aspartate oxidase

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SYSTEMATIC NAME
IUBMB Comments
L-aspartate:oxygen oxidoreductase
A flavoprotein (FAD). L-Aspartate oxidase catalyses the first step in the de novo biosynthesis of NAD+ in some bacteria. O2 can be replaced by fumarate as electron acceptor, yielding succinate [5]. The ability of the enzyme to use both O2 and fumarate in cofactor reoxidation enables it to function under both aerobic and anaerobic conditions [5]. Iminosuccinate can either be hydrolysed to form oxaloacetate and NH3 or can be used by EC 2.5.1.72, quinolinate synthase, in the production of quinolinate. The enzyme is a member of the succinate dehydrogenase/fumarate-reductase family of enzymes [5].