1.4.3.2: L-amino-acid oxidase

This is an abbreviated version, for detailed information about L-amino-acid oxidase, go to the full flat file.

Reaction

an L-amino acid
+
H2O
+
O2
=
a 2-oxo carboxylate
+
NH3
+
H2O2

Synonyms

AAD, ACTX-6, ACTX-8, Akbu-LAAO, APIT, aromatic L-amino acid oxidase, Balt-LAAO-I, Bpir-LAOO-1, DAA, Dolabellanin, escapin, IL4I1, Il4i1 protein, ink toxin 1, Interleukin Four Induced Gene 1 protein, L-AAO, L-AAO/MOG, L-AAO1, L-amino acid oxidase, L-amino acid: O2 oxidoreductase, L-amino acid:O2 oxidoreductase, L-amino acid:O2 oxidoreductase (deaminating), L-aminooxidase, L-Aox, L-phenylalanine oxidase, LAAO, LAAO-I, LAAO-II, LAAO1, LAAOI, LAAOII, LAO, M-LAO, ophio-amino-acid oxidase, Pm1, RoLAAO, sarA, Sebastes schlegeli antibacterial protein, Sebastes schlegelii antibacterial protein, SSAP, TJ-LAO, toxophallin, TSV-LAO

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.2 L-amino-acid oxidase

Natural Substrates Products

Natural Substrates Products on EC 1.4.3.2 - L-amino-acid oxidase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
an L-amino acid + H2O + O2
a 2-oxo-acid + NH3 + H2O2
show the reaction diagram
-
L-amino-acid oxidase catalyzes the oxidative deamination of a number of L-amino acids to their respective imino acids with concomitant hydrolysis to alpha-keto acids, together with the production of ammonia and hydrogen peroxide
-
-
?
bovine serum albumin + H2O + O2
?
show the reaction diagram
-
37% activity compared to L-Lys
-
-
?
casein + H2O + O2
?
show the reaction diagram
-
59% activity compared to L-Lys
-
-
?
DL-asparagine + H2O + O2
2-oxosuccinamic acid + NH3 + H2O2
show the reaction diagram
-
low activity
-
-
?
DL-leucine + H2O + O2
2-oxo-4-methylpentanoate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
DL-methionine + H2O + O2
4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
DL-norleucine + H2O + O2
2-oxocaproate + NH3 + H2O2
show the reaction diagram
DL-threonine + H2O + O2
2-oxo-3-hydroxybutanoic acid + NH3 + H2O2
show the reaction diagram
-
low activity
-
-
?
DL-tryptophan + H2O + O2
3-(1H-indol-3-yl)-2-oxopropanoic acid + NH3 + H2O2
show the reaction diagram
-
low activity
-
-
?
DL-valine + H2O + O2
2-oxoisovalerate + NH3 + H2O2
show the reaction diagram
-
low activity
-
-
?
glutathione + H2O + O2
?
show the reaction diagram
-
97% activity compared to L-Lys
-
-
?
Gly + H2O + O2
glyoxylate + NH3 + H2O2
show the reaction diagram
-
17.8% activity compared to L-Lys
-
-
?
L-Ala + H2O + O2
2-oxo-3-propanoate + NH3 + H2O2
show the reaction diagram
-
lowest activity
-
-
?
L-Ala + H2O + O2
2-oxocaproate + NH3 + H2O2
show the reaction diagram
-
21.2% activity compared to L-Lys
-
-
?
L-Ala + H2O + O2
2-oxopropanoic acid + NH3 + H2O2
show the reaction diagram
L-amino acid + H2O + O2
2-oxo acid + NH3 + H2O2
show the reaction diagram
L-amino acid + H2O + O2
2-oxocarboxylate + NH3 + H2O2
show the reaction diagram
L-amino acid + H2O + O2
a 2-oxo carboxylate + NH3 + H2O2
show the reaction diagram
L-Arg + H2O + O2
2-oxo-5-guanidinopentanoic acid + NH3 + H2O2
show the reaction diagram
Bacillus carotarum
-
-
-
-
?
L-Arg + H2O + O2
2-oxo-5-guanidinovaleric acid + NH3 + H2O2
show the reaction diagram
L-Arg + H2O + O2
5-guanidino-2-oxopentanoic acid + NH3 + H2O2
show the reaction diagram
W6JQJ6
-
-
-
?
L-arginine + H2O + O2
2-oxo-5-guanidinopentanoic acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-Asn + H2O + O2
2-oxosuccinamic acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-Asp + H2O + O2
oxaloacetate + NH3 + H2O2
show the reaction diagram
L-Cys + H2O + O2
2-oxo-3-mercaptopropanoic acid + NH3 + H2O2
show the reaction diagram
L-Gln + H2O + O2
2-glutarate + NH3 + H2O2
show the reaction diagram
L-Gln + H2O + O2
2-oxoglutarate + NH3 + H2O2
show the reaction diagram
L-Glu + H2O + O2
2-oxoglutarate + NH3 + H2O2
show the reaction diagram
L-glutamic acid + H2O + O2
2-oxoglutarate + NH3 + H2O2
show the reaction diagram
L-glutamine + H2O + O2
2-oxo-4-carbamoylbutanoic acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-His + H2O + O2
2-oxo-4-imidazolepropionic acid + NH3 + H2O2
show the reaction diagram
L-histidine + H2O + O2
2-oxo-4-imidazolepropionic acid + NH3 + H2O2
show the reaction diagram
-
low activity
-
-
?
L-Ile + H2O + O2
3-methyl-2-oxo-pentanoic acid + NH3 + H2O2
show the reaction diagram
L-isoleucine + H2O + O2
3-methyl-2-oxopentanoate + NH3 + H2O2
show the reaction diagram
L-Leu + H2O + O2
2-oxo-4-methylvaleric acid + NH3 + H2O2
show the reaction diagram
L-Leu + H2O + O2
4-methyl-2-oxopentanoic acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-leucine + H2O + O2
2-oxo-4-methylpentanoate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-leucine + H2O + O2
2-oxo-4-methylvaleric acid + NH3 + H2O2
show the reaction diagram
L-leucine + H2O + O2
4-methyl-2-oxopentanoic acid + NH3 + H2O2
show the reaction diagram
L-Lys + H2O + O2
6-amino-2-oxo-hexanoic acid + NH3 + H2O2
show the reaction diagram
L-Lys + H2O + O2
6-amino-2-oxohexanoate + NH3 + H2O2
show the reaction diagram
L-Lys + H2O + O2
6-amino-2-oxohexanoic acid + NH3 + H2O2
show the reaction diagram
L-lysine + H2O + O2
6-amino-2-oxohexanoic acid + NH3 + H2O2
show the reaction diagram
L-Met + H2O + O2
4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
show the reaction diagram
L-methionine + H2O + O2
4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
show the reaction diagram
L-Orn + H2O + O2
2-oxo-5-aminopentanoate + NH3 + H2O2
show the reaction diagram
L-Orn + H2O + O2
5-amino-2-oxopentanoic acid + NH3 + H2O2
show the reaction diagram
W6JQJ6
-
-
-
?
L-Phe + H2O + O2
2-oxo-3-phenylpropanoate + NH3 + H2O2
show the reaction diagram
L-Phe + H2O + O2
phenylpyruvate + NH3 + H2O2
show the reaction diagram
L-phenylalanine + H2O + O2
phenylpyruvate + NH3 + H2O2
show the reaction diagram
L-phenylalanine + O2
phenylpyruvate + NH3 + H2O2
show the reaction diagram
-
inhibition of T cell proliferation through phenylalanine degradation
activity measurement by measuring H2O2 production
-
?
L-Pro + H2O + O2
?
show the reaction diagram
-
-
-
-
?
L-Ser + H2O + O2
2-oxo-3-hydroxypropionic acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-Trp + H2O + O2
indol-3-pyruvate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-Trp + H2O + O2
indole-3-pyruvate + NH3 + H2O2
show the reaction diagram
L-tryptophan + H2O + O2
3-(1H-indol-3-yl)-2-oxopropanoate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-tryptophan + H2O + O2
3-(1H-indol-3-yl)-2-oxopropanoic acid + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
L-Tyr + H2O + O2
4-hydroxyphenylpyruvate + NH3 + H2O2
show the reaction diagram
L-tyrosine + H2O + O2
4-hydroxyphenylpyruvate + NH3 + H2O2
show the reaction diagram
L-Val + H2O + O2
2-oxoisovalerate + NH3 + H2O2
show the reaction diagram
L-valine + H2O + O2
2-oxoisovalerate + NH3 + H2O2
show the reaction diagram
-
-
-
-
?
lysine + H2O + O2
6-amino-2-oxohexanoic acid + NH3 + H2O2
show the reaction diagram
-
low activity
-
-
?
additional information
?
-