1.4.3.2: L-amino-acid oxidase

This is an abbreviated version, for detailed information about L-amino-acid oxidase, go to the full flat file.

Reaction

an L-amino acid
+
H2O
+
O2
=
a 2-oxo carboxylate
+
NH3
+
H2O2

Synonyms

AAD, ACTX-6, ACTX-8, Akbu-LAAO, APIT, aromatic L-amino acid oxidase, Balt-LAAO-I, Bpir-LAOO-1, DAA, Dolabellanin, escapin, IL4I1, Il4i1 protein, ink toxin 1, Interleukin Four Induced Gene 1 protein, L-AAO, L-AAO/MOG, L-AAO1, L-amino acid oxidase, L-amino acid: O2 oxidoreductase, L-amino acid:O2 oxidoreductase, L-amino acid:O2 oxidoreductase (deaminating), L-aminooxidase, L-Aox, L-phenylalanine oxidase, LAAO, LAAO-I, LAAO-II, LAAO1, LAAOI, LAAOII, LAO, M-LAO, ophio-amino-acid oxidase, Pm1, RoLAAO, sarA, Sebastes schlegeli antibacterial protein, Sebastes schlegelii antibacterial protein, SSAP, TJ-LAO, toxophallin, TSV-LAO

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.2 L-amino-acid oxidase

pH Range

pH Range on EC 1.4.3.2 - L-amino-acid oxidase

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
3.5 - 12
-
half maximal activity at pH 3.5 and 12
4 - 11
Q8VPD4;
L-phenylalanine as substrate, pH 4: ca. 10% of the activity, pH 11: ca. 60% of the activity
4.5 - 8.5
pH-profile, overview
4.5 - 10.5
5 - 10.4
-
the enzyme shows a slight decrease in its activity at pH 5.0 and 9.6. Actually, the enzyme activity decreases by about 50% of its initial activity at the optimum at acidic pH (3.0) and by less than 3% at alkaline one (pH 10.4)
5.5 - 8.5
-
activity assay range
6 - 10
-
-
7 - 9
-
about 55% activity at pH 7.0, about 85% activity at pH 9.0