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1.4.3.2: L-amino-acid oxidase

This is an abbreviated version!
For detailed information about L-amino-acid oxidase, go to the full flat file.

Word Map on EC 1.4.3.2

Reaction

an L-amino acid
+
H2O
+
O2
=
a 2-oxo carboxylate
+
NH3
+
H2O2

Synonyms

AAD, ACTX-6, ACTX-8, Akbu-LAAO, APIT, apotxin, aromatic L-amino acid oxidase, Balt-LAAO-I, bordonein-L, Bpir-LAOO-1, CC-LPOX, DAA, Dolabellanin, escapin, head kidney and gill, IL4I1, Il4i1 protein, ink toxin 1, Interleukin Four Induced Gene 1 protein, L-AAO, L-AAO/MOG, L-AAO1, L-amino acid oxidase, L-amino acid: O2 oxidoreductase, L-amino acid:O2 oxidoreductase, L-amino acid:O2 oxidoreductase (deaminating), L-aminooxidase, L-Aox, L-phenylalanine oxidase, LAAO, LAAO-1, LAAO-I, LAAO-II, LAAO1, LAAO4, LAAOI, LAAOII, LAO, LAO1, M-LAO, ophio-amino-acid oxidase, Pm1, RoLAAO, sarA, Sebastes schlegeli antibacterial protein, Sebastes schlegelii antibacterial protein, SSAP, TJ-LAO, toxophallin, TSV-LAO

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.2 L-amino-acid oxidase

pH Stability

pH Stability on EC 1.4.3.2 - L-amino-acid oxidase

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pH STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
10
-
4°C, 24 h, complete inactivation
391773
4
-
at a pH below 4, enzymatic activity is completely lost
692650
4 - 9
5
-
4°C, 24 h, complete inactivation
391773
5 - 7
-
the enzyme is stable for 30 min in the pH range from 5.0 to 6.0, but more than 90% of original activity is lost in the alkaline region from pH 7.0
742930
5.5 - 7
-
40°C, 60 min, loss of about 20-30% activity
711874
6 - 9.5
-
the enzyme exhibits a broad pH stability (6.0-9.5), with the highest stability from pH 7.2-7.6 in potassium phosphate buffer
743253
6.5 - 8.8
-
both isoforms retain 100% activity, drastic inactivation above and below this range
692288
7 - 8
-
4°C, 24 h, stable
391773
7 - 8.5
-
40°C, 60 min, highly stable
711874
7.5 - 9.5
purified recombinant enzyme, highly stable at, 55°C, loss of about 50% activity at pH 3.0-6.0, loss of 40% activity at pH 11.0
746344
additional information