1.4.3.5: pyridoxal 5'-phosphate synthase
This is an abbreviated version!
For detailed information about pyridoxal 5'-phosphate synthase, go to the full flat file.
Word Map on EC 1.4.3.5
Reaction
Synonyms
ePNPOx, FprA protein, oxidase, pyridoxamine phosphate, Pdx1, PDX3, PdxH, PMP oxidase, PNP oxidase, PNP/PMP oxidase, PNPO, PNPOx, PPOX, pyridox(am)ine 5'-phosphate oxidase, pyridoxal 5'-phosphate synthase, pyridoxal 5'-phosphate synthetic enzyme, pyridoxamine (pyridoxine) 5'-phosphate oxidase, pyridoxamine (pyridoxine) 5’-phosphate:O2 oxidoreductase (deaminating), pyridoxamine 5'-phosphate oxidase, pyridoxamine phosphate oxidase, pyridoxamine-5-phosphate oxidase, pyridoxamine-phosphate oxidase, pyridoxaminephosphate oxidase (EC 1.4.3.5: deaminating), pyridoxinamine 5'-phosphate oxidase, pyridoxine (pyridoxamine) 5 '-phosphate oxidase, pyridoxine (pyridoxamine) 5'-phosphate oxidase, pyridoxine (pyridoxamine) phosphate oxidase, pyridoxine 5'-phosphate oxidase, pyridoxine 5'-phosphate oxidase`, pyridoxine 5-phosphate oxidase, pyridoxine phosphate oxidase, pyridoxine-5'-phosphate oxidase, pyridoxine/pyridoxamine 5'-phosphate oxidase, pyridoxine/pyridoxamine phosphate oxidase, sgll, Sgll/PNPO, Ylr456w, Ypr172w
ECTree
1.4.3.5 pyridoxal 5'-phosphate synthaseAdvanced search results
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results (Natural Substrates Products
Natural Substrates Products on EC 1.4.3.5 - pyridoxal 5'-phosphate synthase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
pyridoxamine 5'-phosphate + FMN + H2O + 2 H+
pyridoxal 5'-phosphate + FMNH2 + NH3
-
-
-
?
pyridoxamine 5'-phosphate + FMN + H2O + 2 H+
pyridoxal 5'-phosphate + FMNH2 + NH3
-
-
-
-
?
pyridoxamine 5'-phosphate + FMN + H2O + 2 H+
pyridoxal 5'-phosphate + FMNH2 + NH3
-
-
-
-
?
pyridoxamine 5'-phosphate + FMN + H2O + 2 H+
pyridoxal 5'-phosphate + FMNH2 + NH3
-
-
-
-
?
pyridoxamine 5'-phosphate + FMN + H2O + 2 H+
pyridoxal 5'-phosphate + FMNH2 + NH3
-
-
-
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
-
-
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
may be the regulatory enzyme in the final step of pyridoxal 5'-phosphate biosynthesis
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
-
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
may be the regulatory enzyme in the final step of pyridoxal 5'-phosphate biosynthesis
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
may be the regulatory enzyme in the final step of pyridoxal 5'-phosphate biosynthesis
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
may be the regulatory enzyme in the final step of pyridoxal 5'-phosphate biosynthesis
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
-
-
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
terminal step in de novo biosynthesis of pyridoxal 5'-phosphate
-
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
may be the regulatory enzyme in the final step of pyridoxal 5'-phosphate biosynthesis
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
may be the regulatory enzyme in the final step of pyridoxal 5'-phosphate biosynthesis
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
-
-
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
-
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
enzyme plays a role in regulation of vitamin B-6 metabolism in erythrocytes
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
terminal step in de novo biosynthesis of pyridoxal 5'-phosphate
-
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
may be the regulatory enzyme in the final step of pyridoxal 5'-phosphate biosynthesis
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
may be the regulatory enzyme in the final step of pyridoxal 5'-phosphate biosynthesis
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
-
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
-
-
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
-
-
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
-
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
Mycolicibacterium smegmatis mc(2)155 / ATCC 700084
-
-
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
-
-
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
in conjugation with pyridoxal kinase the enzyme is responsible for the formation of the coenzyme pyridoxal 5'-phosphate, from the B6 vitamers pyridoxine and pyridoxamine
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
may be the regulatory enzyme in the final step of pyridoxal 5'-phosphate biosynthesis
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
may be the regulatory enzyme in the final step of pyridoxal 5'-phosphate biosynthesis
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
-
-
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
-
-
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
may be the regulatory enzyme in the final step of pyridoxal 5'-phosphate biosynthesis
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
may be the regulatory enzyme in the final step of pyridoxal 5'-phosphate biosynthesis
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
may be the regulatory enzyme in the final step of pyridoxal 5'-phosphate biosynthesis
-
?
pyridoxamine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + NH3 + H2O2
-
may be the regulatory enzyme in the final step of pyridoxal 5'-phosphate biosynthesis
-
?
pyridoxine 5'-phosphate + FMN
pyridoxal 5'-phosphate + FMNH2
-
-
-
-
?
pyridoxine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + H2O2
-
-
-
-
?
pyridoxine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + H2O2
-
preferred substrate
-
-
?
pyridoxine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + H2O2
-
terminal step in de novo biosynthesis of pyridoxal 5'-phosphate
-
-
?
pyridoxine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + H2O2
-
terminal step in de novo biosynthesis of pyridoxal 5'-phosphate
-
-
?
pyridoxine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + H2O2
-
-
-
-
?
pyridoxine 5'-phosphate + H2O + O2
pyridoxal 5'-phosphate + H2O2
-
-
-
-
?
pyridoxine 5'-phosphate + O2
pyridoxal 5'-phosphate + H2O2
-
the enzyme catalyzes the last step is pyridoxine 5'-phosphate oxidation to pyridoxal 5'-phosphate. The enzyme plays a pivotal role in controlling intracellular homeostasis and bioavailability of pyridoxal 5'-phosphate
-
-
?
pyridoxine 5'-phosphate + O2
pyridoxal 5'-phosphate + H2O2
-
-
-
?
pyridoxine 5'-phosphate + O2
pyridoxal 5'-phosphate + H2O2
-
-
-
?
pyridoxine 5'-phosphate + O2
pyridoxal 5'-phosphate + H2O2
-
-
-
-
?
pyridoxine 5'-phosphate + O2
pyridoxal 5'-phosphate + H2O2
-
-
-
?
pyridoxine 5'-phosphate + O2
pyridoxal 5'-phosphate + H2O2
-
-
-
-
?
pyridoxine 5'-phosphate + O2
pyridoxal 5'-phosphate + H2O2
-
-
-
?
pyridoxine 5'-phosphate + O2
pyridoxal 5'-phosphate + H2O2
Mycolicibacterium smegmatis mc(2)155 / ATCC 700084
-
-
-
?
additional information
?
-
-
mutations in the PNPO gene encoding pyridox(am)ine 5'-phosphate oxidase cause neonatal epileptic encephalopathy
-
-
?
additional information
?
-
-
the enzyme does not recognize pyridoxamine 5'-phosphate as substrate
-
-
?
additional information
?
-
-
the enzyme does not recognize pyridoxamine 5'-phosphate as substrate
-
-
?
