1.5.1.15: methylenetetrahydrofolate dehydrogenase (NAD+)

This is an abbreviated version, for detailed information about methylenetetrahydrofolate dehydrogenase (NAD+), go to the full flat file.

Reaction

5,10-methylenetetrahydrofolate
+
NAD+
=
5,10-methenyltetrahydrofolate
 +
NADH
 +
H+

Synonyms

5,10-methylenetetrahydrofolate reductase, bifunctional N5,N10-methylene-H4F dehydrogenase/N5,N10-methenyltetrahydrofolate cyclohydrolase, FolD, methylenetetrahydrofolate dehydrogenase-cyclohydrolase, methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase, methylenetetrahydrofolate reductase, methyleneTHF dehydrogenase, Mg2+-/phosphate-dependent dehydrogenase, Mg2+/NAD-dependent methylenetetrahydrofolate dehydrogenase, More, MTD, MTHFR, NAD+-dependent methylene-H4F dehydrogenase, NAD-dependent dehydrogenase-cyclohydrolase, NMDMC

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.15 methylenetetrahydrofolate dehydrogenase (NAD+)