1.5.1.2: pyrroline-5-carboxylate reductase

This is an abbreviated version!
For detailed information about pyrroline-5-carboxylate reductase, go to the full flat file.

Word Map on EC 1.5.1.2

Reaction

L-proline
+
NAD(P)+
=
1-pyrroline-5-carboxylate
+
NAD(P)H
+
H+

Synonyms

1-pyrroline-5-carboxylate reductase, DELTA1-pyrroline-5-carboxylate reductase, L-proline oxidase, L-proline-NAD(P)+ 5-oxidoreductase, L-proline:NAD(P)+ 5-oxidoreductase, MTR_7g090160, NADPH-L-DELTA'-pyrroline carboxylic acid reductase, P5C reductase, P5CDH, P5CR, PO, POX, proline oxidase, Pycr1, pyrroline-5-carboxylate dehydrogenase, pyrroline-5-carboxylate reductase, reductase, pyrroline-5-carboxylate

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.2 pyrroline-5-carboxylate reductase

Natural Substrates Products

Natural Substrates Products on EC 1.5.1.2 - pyrroline-5-carboxylate reductase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
1-pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
show the reaction diagram
1-pyrroline-5-carboxylate + NADPH + H+
L-proline + NADP+
show the reaction diagram
DELTA1-pyrroline-5-carboxylate + NADH + H+
L-proline + NAD+
show the reaction diagram
O87725
-
-
-
r
L-Pro + NAD(P)+
1-pyrroline-5-carboxylate + NAD(P)H
show the reaction diagram
-
the enzyme plays a role as a downstream effector in p53-mediated apoptosis of renal carcinoma cells
-
-
-
L-proline + NAD(P)+
1-pyrroline-5-carboxylate + NAD(P)H + H+
show the reaction diagram
L-proline + NADP+
1-pyrroline-5-carboxylate + NADPH + H+
show the reaction diagram
pyrroline-5-carboxylate + NAD(P)H + H+
L-proline + NAD(P)+
show the reaction diagram