1.5.1.21: 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)

This is an abbreviated version!
For detailed information about 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH), go to the full flat file.

Word Map on EC 1.5.1.21

Reaction

L-pipecolate
+
NADP+
=
1-piperideine-2-carboxylate
+
NADPH
+
H+

Synonyms

1,2-didehydropipecolate reductase, 1,2-didehydropipecolic reductase, CRYM, DELTA1-piperideine-2-carboxylate reductase, DELTA1-piperideine-2-carboxylate/DELTA1-pyrroline-2-carboxylate reductase, DELTA1-pyrroline-2-carboxylate reductase, DpkA, EC 1.5.1.14, ketimine reductase, L-pipecolate:NADP+ 2-oxidoreductase, lhpD, mu-crystallin, NAD(P)H-dependent DELTA1-pyrroline-2-carboxylate reductase, P2C reductase, P2C/Pyr2C reductase, PaLhpD, Pip2CR, Pyr2C reductase, Pyr2C/Pip2C reductase, reductase, DELTA 1-piperideine-2-carboxylate

ECTree

     1 Oxidoreductases
         1.5 Acting on the CH-NH group of donors
             1.5.1 With NAD+ or NADP+ as acceptor
                1.5.1.21 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)

Disease

Disease on EC 1.5.1.21 - 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Deafness
CRYM mutations cause deafness through thyroid hormone binding properties in the fibrocytes of the cochlea.
mu-crystallin, a NADPH-dependent T(3)-binding protein in cytosol.
Spiking Expression of mu-Crystallin mRNA during Treatment with Methimazole in Patients with Graves' Hyperthyroidism.
Glioblastoma
Biomarker discovery: a proteomic approach for brain cancer profiling.
Hearing Loss
CRYM mutations cause deafness through thyroid hormone binding properties in the fibrocytes of the cochlea.
Hyperthyroidism
Spiking Expression of mu-Crystallin mRNA during Treatment with Methimazole in Patients with Graves' Hyperthyroidism.
Muscular Diseases
Abnormal expression of mu-crystallin in facioscapulohumeral muscular dystrophy.
Muscular Dystrophies
Abnormal expression of mu-crystallin in facioscapulohumeral muscular dystrophy.
Muscular Dystrophy, Facioscapulohumeral
Abnormal expression of mu-crystallin in facioscapulohumeral muscular dystrophy.
Neoplasms
Moderate-Intensity Exercise Induces Neurogenesis and Improves Cognition in Old Mice by Upregulating Hippocampal Hippocalcin, Otub1, and Spectrin-?.
Spinal Cord Injuries
Comprehensive Corticospinal Labeling with mu-crystallin Transgene Reveals Axon Regeneration after Spinal Cord Trauma in ngr1-/- Mice.